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APMAP adipocyte plasma membrane associated protein [ Homo sapiens (human) ]

Gene ID: 57136, updated on 5-May-2024

Summary

Official Symbol
APMAPprovided by HGNC
Official Full Name
adipocyte plasma membrane associated proteinprovided by HGNC
Primary source
HGNC:HGNC:13238
See related
Ensembl:ENSG00000101474 MIM:615884; AllianceGenome:HGNC:13238
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BSCv; C20orf3
Summary
Enables arylesterase activity. Predicted to be involved in biosynthetic process. Located in cell surface and membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in thyroid (RPKM 46.5), fat (RPKM 34.1) and 24 other tissues See more
Orthologs
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Genomic context

Location:
20p11.21
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 20 NC_000020.11 (24962925..24992751, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 20 NC_060944.1 (25027196..25056965, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (24943561..24973387, complement)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:24899137-24899770 Neighboring gene long intergenic non-protein coding RNA 2967 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17652 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17653 Neighboring gene cystatin F Neighboring gene RNA, U6 small nuclear 1257, pseudogene Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:24960021-24960521 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr20:24961283-24961783 Neighboring gene H3K27ac hESC enhancers GRCh37_chr20:24972940-24973440 and GRCh37_chr20:24973441-24973941 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17657 Neighboring gene acyl-CoA synthetase short chain family member 1 Neighboring gene Sharpr-MPRA regulatory region 14776 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12738 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17658 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 17659 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 12739 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr20:25038651-25039256 Neighboring gene uncharacterized LOC124904882

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables arylesterase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables arylesterase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables strictosidine synthase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cell surface IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane HDA PubMed 
located_in membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
adipocyte plasma membrane-associated protein
Names
protein BSCv

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_020531.3NP_065392.1  adipocyte plasma membrane-associated protein

    See identical proteins and their annotated locations for NP_065392.1

    Status: VALIDATED

    Source sequence(s)
    AK026866, AL035661, BG773501, CF131759
    Consensus CDS
    CCDS13166.1
    UniProtKB/Swiss-Prot
    A8K514, B4DXG1, Q6UVZ8, Q9GZS8, Q9HDC9, Q9NUB2
    UniProtKB/TrEMBL
    H0Y512
    Related
    ENSP00000217456.2, ENST00000217456.3
    Conserved Domains (4) summary
    COG3386
    Location:73320
    YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
    cd05819
    Location:102137
    NHL; NHL repeat [structural motif]
    cl18310
    Location:96284
    NHL; NHL repeat unit of beta-propeller proteins
    cl22863
    Location:201288
    Str_synth; Strictosidine synthase

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000020.11 Reference GRCh38.p14 Primary Assembly

    Range
    24962925..24992751 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005260763.4XP_005260820.1  adipocyte plasma membrane-associated protein isoform X1

    UniProtKB/Swiss-Prot
    Q9HDC9
    Conserved Domains (3) summary
    cd05819
    Location:102137
    NHL; NHL repeat [structural motif]
    cl18310
    Location:96282
    NHL; NHL repeat unit of beta-propeller proteins
    cl22863
    Location:201287
    Str_synth; Strictosidine synthase

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060944.1 Alternate T2T-CHM13v2.0

    Range
    25027196..25056965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054323725.1XP_054179700.1  adipocyte plasma membrane-associated protein isoform X1