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LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 718249, updated on 17-Aug-2024

Summary

Official Symbol
LAMTOR1provided by VGNC
Official Full Name
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1provided by VGNC
Primary source
VGNC:VGNC:74129
Locus tag
EGK_06642
See related
Ensembl:ENSMMUG00000021282
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
C11orf59
Orthologs
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Genomic context

Location:
chromosome: 14
Exon count:
6
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (65036892..65055207, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (64014798..64021199, complement)

Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene interleukin 18 binding protein Neighboring gene nuclear mitotic apparatus protein 1 Neighboring gene U6 spliceosomal RNA Neighboring gene leucine rich transmembrane and O-methyltransferase domain containing Neighboring gene small nucleolar RNA U13 Neighboring gene anaphase promoting complex subunit 15

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables molecular adaptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to amino acid stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cholesterol homeostasis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in endosomal transport IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in lysosome organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of TOR signaling IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of receptor recycling IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of Ragulator complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in late endosome membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
ragulator complex protein LAMTOR1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001194634.3NP_001181563.1  ragulator complex protein LAMTOR1

    See identical proteins and their annotated locations for NP_001181563.1

    Status: PROVISIONAL

    Source sequence(s)
    QNVO02000111
    UniProtKB/TrEMBL
    A0A1D5QXH4, A0A8J8YAD4, G7NE86, H9ELW8
    Related
    ENSMMUP00000076869.1, ENSMMUT00000094427.1
    Conserved Domains (1) summary
    pfam15454
    Location:2185
    LAMTOR; Late endosomal/lysosomal adaptor and MAPK and MTOR activator

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041767.1 Reference Mmul_10 Primary Assembly

    Range
    65036892..65055207 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028832842.1XP_028688675.1  ragulator complex protein LAMTOR1 isoform X1

    Conserved Domains (1) summary
    pfam15454
    Location:1883
    LAMTOR; Late endosomal/lysosomal adaptor and MAPK and MTOR activator