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Sanbr SANT and BTB domain regulator of CSR [ Mus musculus (house mouse) ]

Gene ID: 71675, updated on 5-Mar-2024

Summary

Official Symbol
Sanbrprovided by MGI
Official Full Name
SANT and BTB domain regulator of CSRprovided by MGI
Primary source
MGI:MGI:1918925
See related
Ensembl:ENSMUSG00000042208 AllianceGenome:MGI:1918925
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Kiaa1841; mKIAA1841; 0610010F05Rik
Summary
Is expressed in central nervous system; ganglia; and sensory organ. Orthologous to human SANBR (SANT and BTB domain regulator of CSR). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E18 (RPKM 9.0), CNS E14 (RPKM 7.6) and 14 other tissues See more
Orthologs
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Genomic context

See Sanbr in Genome Data Viewer
Location:
11 A3.2; 11 14.33 cM
Exon count:
28
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (23514949..23596409, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (23564949..23633681, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700093K21 gene Neighboring gene STARR-seq mESC enhancer starr_28914 Neighboring gene STARR-seq mESC enhancer starr_28915 Neighboring gene STARR-seq mESC enhancer starr_28916 Neighboring gene STARR-seq mESC enhancer starr_28917 Neighboring gene selenoprotein K, pseudogene 1 Neighboring gene peroxisomal biogenesis factor 13 Neighboring gene pseudouridylate synthase 10 Neighboring gene STARR-seq mESC enhancer starr_28923 Neighboring gene reticuloendotheliosis oncogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding IDA
Inferred from Direct Assay
more info
PubMed 
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in isotype switching IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
SANT and BTB domain regulator of class switch recombination

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001347242.1NP_001334171.1  SANT and BTB domain regulator of class switch recombination isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 2, which is shorter at the N-terminus, compared to isoform 1.
    Source sequence(s)
    AI642567, AL672049
    Consensus CDS
    CCDS88137.1
    UniProtKB/Swiss-Prot
    Q68FF0
    Conserved Domains (1) summary
    pfam11822
    Location:1102
    DUF3342; Domain of unknown function (DUF3342)
  2. NM_027860.3NP_082136.2  SANT and BTB domain regulator of class switch recombination isoform 1

    See identical proteins and their annotated locations for NP_082136.2

    Status: VALIDATED

    Source sequence(s)
    AK053838, BB522605, BC072622, BC079876, BP759684
    Consensus CDS
    CCDS36119.1
    UniProtKB/Swiss-Prot
    A2AF87, A2AF88, A2AF89, A2AF91, A2AF92, Q3UQL0, Q68FF0, Q6GQU5, Q6ZPH2, Q8BPK6, Q9CWA7
    Related
    ENSMUSP00000136118.2, ENSMUST00000180260.8
    Conserved Domains (1) summary
    pfam11822
    Location:147248
    DUF3342; Domain of unknown function (DUF3342)

RNA

  1. NR_156450.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL672049

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    23514949..23596409 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156994.1XP_036012887.1  SANT and BTB domain regulator of class switch recombination isoform X3

    Conserved Domains (1) summary
    pfam11822
    Location:147248
    DUF3342; Domain of unknown function (DUF3342)
  2. XM_006514811.5XP_006514874.1  SANT and BTB domain regulator of class switch recombination isoform X3

    Conserved Domains (1) summary
    pfam11822
    Location:147248
    DUF3342; Domain of unknown function (DUF3342)
  3. XM_036156993.1XP_036012886.1  SANT and BTB domain regulator of class switch recombination isoform X2

    UniProtKB/TrEMBL
    M0QWF3
    Related
    ENSMUSP00000137799.2, ENSMUST00000155903.8
    Conserved Domains (1) summary
    pfam11822
    Location:147248
    DUF3342; Domain of unknown function (DUF3342)
  4. XM_036156995.1XP_036012888.1  SANT and BTB domain regulator of class switch recombination isoform X4

    Conserved Domains (1) summary
    pfam11822
    Location:147248
    DUF3342; Domain of unknown function (DUF3342)
  5. XM_017314769.3XP_017170258.1  SANT and BTB domain regulator of class switch recombination isoform X4

    Conserved Domains (1) summary
    pfam11822
    Location:147248
    DUF3342; Domain of unknown function (DUF3342)
  6. XM_006514808.4XP_006514871.1  SANT and BTB domain regulator of class switch recombination isoform X1

    See identical proteins and their annotated locations for XP_006514871.1

    UniProtKB/Swiss-Prot
    A2AF87, A2AF88, A2AF89, A2AF91, A2AF92, Q3UQL0, Q68FF0, Q6GQU5, Q6ZPH2, Q8BPK6, Q9CWA7
    Conserved Domains (1) summary
    pfam11822
    Location:147248
    DUF3342; Domain of unknown function (DUF3342)
  7. XM_030246329.1XP_030102189.1  SANT and BTB domain regulator of class switch recombination isoform X5

    Related
    ENSMUSP00000090955.5, ENSMUST00000093267.11
    Conserved Domains (1) summary
    pfam11822
    Location:1102
    DUF3342; Domain of unknown function (DUF3342)
  8. XM_030246327.1XP_030102187.1  SANT and BTB domain regulator of class switch recombination isoform X1

    UniProtKB/Swiss-Prot
    A2AF87, A2AF88, A2AF89, A2AF91, A2AF92, Q3UQL0, Q68FF0, Q6GQU5, Q6ZPH2, Q8BPK6, Q9CWA7
    Related
    ENSMUSP00000044265.7, ENSMUST00000043356.13
    Conserved Domains (1) summary
    pfam11822
    Location:147248
    DUF3342; Domain of unknown function (DUF3342)
  9. XM_011243749.3XP_011242051.1  SANT and BTB domain regulator of class switch recombination isoform X1

    See identical proteins and their annotated locations for XP_011242051.1

    UniProtKB/Swiss-Prot
    A2AF87, A2AF88, A2AF89, A2AF91, A2AF92, Q3UQL0, Q68FF0, Q6GQU5, Q6ZPH2, Q8BPK6, Q9CWA7
    Conserved Domains (1) summary
    pfam11822
    Location:147248
    DUF3342; Domain of unknown function (DUF3342)
  10. XM_017314768.3XP_017170257.1  SANT and BTB domain regulator of class switch recombination isoform X1

    UniProtKB/Swiss-Prot
    A2AF87, A2AF88, A2AF89, A2AF91, A2AF92, Q3UQL0, Q68FF0, Q6GQU5, Q6ZPH2, Q8BPK6, Q9CWA7
    Conserved Domains (1) summary
    pfam11822
    Location:147248
    DUF3342; Domain of unknown function (DUF3342)

RNA

  1. XR_004937036.1 RNA Sequence