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Utp20 UTP20 small subunit processome component [ Mus musculus (house mouse) ]

Gene ID: 70683, updated on 17-Aug-2024

Summary

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Official Symbol
Utp20provided by MGI
Official Full Name
UTP20 small subunit processome componentprovided by MGI
Primary source
MGI:MGI:1917933
See related
Ensembl:ENSMUSG00000004356 AllianceGenome:MGI:1917933
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Drim; mDRIM; mDRIN; 3830408P06Rik
Summary
Predicted to be involved in rRNA processing. Predicted to be located in plasma membrane. Predicted to be part of 90S preribosome and small-subunit processome. Predicted to be active in nucleolus. Is expressed in cerebellum; retina inner nuclear layer; and retina outer nuclear layer. Orthologous to human UTP20 (UTP20 small subunit processome component). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 4.2), limb E14.5 (RPKM 2.9) and 25 other tissues See more
Orthologs
human all
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Genomic context

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Location:
10 C1; 10 44.21 cM
Exon count:
62
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (88582469..88662676, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (88746607..88826814, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_27509 Neighboring gene STARR-positive B cell enhancer ABC_E11454 Neighboring gene predicted gene, 46192 Neighboring gene predicted gene 4925 Neighboring gene STARR-seq mESC enhancer starr_27512 Neighboring gene ADP-ribosylation factor-like 1 Neighboring gene STARR-seq mESC enhancer starr_27513 Neighboring gene solute carrier family 5 (iodide transporter), member 8 Neighboring gene STARR-seq mESC enhancer starr_27514 Neighboring gene STARR-seq mESC enhancer starr_27515 Neighboring gene anoctamin 4 Neighboring gene predicted gene, 30769

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Isolation of novel mouse genes that were differentially expressed in W/W(V) mouse fundus. Daigo Y, et al. J Gastroenterol, 2004. PMID 15065000
  2. Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation. Varum S, et al. Cell Stem Cell, 2019 Apr 4. PMID 30951662
  3. Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner. Zurkirchen L, et al. Nat Commun, 2019 May 16. PMID 31097699, Free PMC Article
  4. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
  5. The central role of EED in the orchestration of polycomb group complexes. Cao Q, et al. Nat Commun, 2014. PMID 24457600, Free PMC Article

See all (20) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in rRNA processing ISO
Inferred from Sequence Orthology
more info
  
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
part_of 90S preribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
small subunit processome component 20 homolog
Names
UTP20, small subunit (SSU) processome component, homolog
down-regulated in metastasis protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175158.3 → NP_780367.2  small subunit processome component 20 homolog

    Status: VALIDATED

    Source sequence(s)
    AC155820, AC164567
    Consensus CDS
    CCDS48667.1
    UniProtKB/Swiss-Prot
    Q5XG71, Q80V22, Q8BXH9, Q8CHL6, Q99K11
    UniProtKB/TrEMBL
    E9QK83
    Related
    ENSMUSP00000004470.8, ENSMUST00000004470.9
    Conserved Domains (1) summary
    pfam07539
    Location:912 → 1531
    DRIM; Down-regulated in metastasis

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    88582469..88662676 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5XG71.2 GenPept UniProtKB/Swiss-Prot:Q5XG71

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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Chemical Information
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