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Btf3l4 basic transcription factor 3-like 4 [ Mus musculus (house mouse) ]

Gene ID: 70533, updated on 2-Nov-2024

Summary

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Official Symbol
Btf3l4provided by MGI
Official Full Name
basic transcription factor 3-like 4provided by MGI
Primary source
MGI:MGI:1915312
See related
Ensembl:ENSMUSG00000028568 AllianceGenome:MGI:1915312
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4632412E09Rik; 5730434I03Rik
Summary
Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human BTF3L4 (basic transcription factor 3 like 4). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in CNS E14 (RPKM 19.6), whole brain E14.5 (RPKM 19.2) and 23 other tissues See more
Orthologs
human all
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Genomic context

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See Btf3l4 in Genome Data Viewer
Location:
4 C7; 4 50.64 cM
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (108671489..108691445, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (108814295..108834302, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene zinc finger, FYVE domain containing 9 Neighboring gene ribosomal protein L9 pseudogene Neighboring gene predicted gene, 53266 Neighboring gene STARR-seq mESC enhancer starr_11051 Neighboring gene STARR-seq mESC enhancer starr_11052 Neighboring gene STARR-positive B cell enhancer mm9_chr4:108520274-108520575 Neighboring gene thioredoxin domain containing 12 (endoplasmic reticulum) Neighboring gene KTI12 homolog, chromatin associated Neighboring gene RAB3B, member RAS oncogene family Neighboring gene STARR-seq mESC enhancer starr_11058 Neighboring gene RIKEN cDNA 8030443G20 gene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set. VanBuren V, et al. Genome Res, 2002 Dec. PMID 12466305, Free PMC Article
  2. Genomic analysis of mouse retinal development. Blackshaw S, et al. PLoS Biol, 2004 Sep. PMID 15226823, Free PMC Article
  3. Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies. Murtaza N, et al. Cell Rep, 2022 Nov 22. PMID 36417873
  4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
  5. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article

See all (25) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
transcription factor BTF3 homolog 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356361.2 → NP_001343290.1  transcription factor BTF3 homolog 4 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL607070
    Consensus CDS
    CCDS18456.1
    UniProtKB/Swiss-Prot
    Q9CQH7
    UniProtKB/TrEMBL
    A2A7Z4, Q78IG7
    Conserved Domains (1) summary
    cd22055
    Location:4 → 120
    NAC_BTF3; basal transcription factor BTF3

  2. NM_001404469.1 → NP_001391398.1  transcription factor BTF3 homolog 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL607070
    UniProtKB/Swiss-Prot
    Q9CQH7
    UniProtKB/TrEMBL
    A2A7Z4

  3. NM_001404470.1 → NP_001391399.1  transcription factor BTF3 homolog 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL607070
    UniProtKB/Swiss-Prot
    Q9CQH7
    UniProtKB/TrEMBL
    A2A7Z4
    Related
    ENSMUSP00000099802.2, ENSMUST00000102741.8

  4. NM_001404471.1 → NP_001391400.1  transcription factor BTF3 homolog 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL607070
    UniProtKB/Swiss-Prot
    Q9CQH7
    UniProtKB/TrEMBL
    A2A7Z4

  5. NM_001404472.1 → NP_001391401.1  transcription factor BTF3 homolog 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL607070
    UniProtKB/Swiss-Prot
    Q9CQH7
    UniProtKB/TrEMBL
    A2A7Z4
    Related
    ENSMUSP00000099801.2, ENSMUST00000102740.8

  6. NM_001404473.1 → NP_001391402.1  transcription factor BTF3 homolog 4 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AL607070
    UniProtKB/Swiss-Prot
    Q9CQH7
    UniProtKB/TrEMBL
    A2A7Z4
    Related
    ENSMUSP00000099800.2, ENSMUST00000102739.2

  7. NM_001404474.1 → NP_001391403.1  transcription factor BTF3 homolog 4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL607070

  8. NM_001404475.1 → NP_001391404.1  transcription factor BTF3 homolog 4 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AL607070

  9. NM_001404476.1 → NP_001391405.1  transcription factor BTF3 homolog 4 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL607070

  10. NM_001404477.1 → NP_001391406.1  transcription factor BTF3 homolog 4 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL607070

  11. NM_001404478.1 → NP_001391407.1  transcription factor BTF3 homolog 4 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL607070

  12. NM_001404479.1 → NP_001391408.1  transcription factor BTF3 homolog 4 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL607070

  13. NM_001404480.1 → NP_001391409.1  transcription factor BTF3 homolog 4 isoform 5

    Status: VALIDATED

    Source sequence(s)
    AL607070

  14. NM_001404481.1 → NP_001391410.1  transcription factor BTF3 homolog 4 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AL607070

  15. NM_001404482.1 → NP_001391411.1  transcription factor BTF3 homolog 4 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AL607070

  16. NM_001404483.1 → NP_001391412.1  transcription factor BTF3 homolog 4 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AL607070

  17. NM_001404484.1 → NP_001391413.1  transcription factor BTF3 homolog 4 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AL607070

  18. NM_001404486.1 → NP_001391415.1  transcription factor BTF3 homolog 4 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AL607070

  19. NM_001404487.1 → NP_001391416.1  transcription factor BTF3 homolog 4 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AL607070

  20. NM_001404488.1 → NP_001391417.1  transcription factor BTF3 homolog 4 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AL607070

  21. NM_001404489.1 → NP_001391418.1  transcription factor BTF3 homolog 4 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AL607070

  22. NM_027453.4 → NP_081729.1  transcription factor BTF3 homolog 4 isoform 1

    See identical proteins and their annotated locations for NP_081729.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AL607070
    Consensus CDS
    CCDS18456.1
    UniProtKB/Swiss-Prot
    Q9CQH7
    UniProtKB/TrEMBL
    A2A7Z4, Q78IG7
    Related
    ENSMUSP00000099803.5, ENSMUST00000102742.11
    Conserved Domains (1) summary
    cd22055
    Location:4 → 120
    NAC_BTF3; basal transcription factor BTF3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    108671489..108691445 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CQH7.1 GenPept UniProtKB/Swiss-Prot:Q9CQH7

Gene LinkOut

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