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Ino80b INO80 complex subunit B [ Mus musculus (house mouse) ]

Gene ID: 70020, updated on 5-Mar-2024

Summary

Official Symbol
Ino80bprovided by MGI
Official Full Name
INO80 complex subunit Bprovided by MGI
Primary source
MGI:MGI:1917270
See related
Ensembl:ENSMUSG00000030034 AllianceGenome:MGI:1917270
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Papa1; Znhit4; HMG1YL4; Hmga1l4; 2510009I23Rik
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in chromatin remodeling. Predicted to act upstream of or within DNA recombination and DNA repair. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of Ino80 complex. Is expressed in Harderian gland; duodenum; metanephros; oviduct; and uterus. Orthologous to human INO80B (INO80 complex subunit B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 45.4), duodenum adult (RPKM 39.6) and 28 other tissues See more
Orthologs
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Genomic context

See Ino80b in Genome Data Viewer
Location:
6 C3; 6 35.94 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (83098746..83102100, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (83121765..83125119, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6446 Neighboring gene mannosyl-oligosaccharide glucosidase Neighboring gene STARR-positive B cell enhancer ABC_E344 Neighboring gene WW domain binding protein 1 Neighboring gene STARR-positive B cell enhancer ABC_E9669 Neighboring gene rhotekin Neighboring gene WD repeat domain 54

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
part_of Ino80 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Ino80 complex ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
INO80 complex subunit B
Names
PAP-1 binding protein
PAP-1-associated protein 1
PAPA-1
high mobility group AT-hook 1-like 4
zinc finger HIT domain-containing protein 4
zinc finger, HIT type 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023547.2NP_076036.2  INO80 complex subunit B

    Status: VALIDATED

    Source sequence(s)
    AC104324
    Consensus CDS
    CCDS39530.1
    UniProtKB/TrEMBL
    A0A6Q6QAE5, Q80ZV5
    Related
    ENSMUSP00000032109.5, ENSMUST00000032109.5
    Conserved Domains (2) summary
    pfam04795
    Location:211289
    PAPA-1; PAPA-1-like conserved region
    pfam04438
    Location:307338
    zf-HIT; HIT zinc finger

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    83098746..83102100 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)