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TDGF1P3 teratocarcinoma-derived growth factor 1 pseudogene 3 [ Homo sapiens (human) ]

Gene ID: 6998, updated on 12-Oct-2019

Summary

Official Symbol
TDGF1P3provided by HGNC
Official Full Name
teratocarcinoma-derived growth factor 1 pseudogene 3provided by HGNC
Primary source
HGNC:HGNC:11703
See related
Ensembl:ENSG00000225366
Gene type
pseudo
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CR-3; TDGF1; TDGF2; TDGF3; CRIPTO; CRIPTO3; CRIPTO-3
Summary
The TDGF3 locus has characteristics of a retrotransposon, including lack of introns and a poly(A) sequence. [provided by RefSeq, Jul 2008]

Genomic context

See TDGF1P3 in Genome Data Viewer
Location:
Xq23
Exon count:
1
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (110520312..110523021)
105 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (109763540..109766249)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene AMMECR nuclear protein 1 Neighboring gene G protein subunit gamma 5 pseudogene 2 Neighboring gene retrotransposon Gag like 9 Neighboring gene mannose-6-phosphate receptor, cation dependent pseudogene Neighboring gene chordin like 1

Genomic regions, transcripts, and products

Pathways from BioSystems

  • Developmental Biology, organism-specific biosystem (from REACTOME)
    Developmental Biology, organism-specific biosystemAs a first step towards capturing the array of processes by which a fertilized egg gives rise to the diverse tissues of the body, examples of three kinds of processes have been annotated. These are a...
  • Regulation of signaling by NODAL, organism-specific biosystem (from REACTOME)
    Regulation of signaling by NODAL, organism-specific biosystemMature NODAL can form heterodimers with LEFTY1, LEFTY2, or CERBERUS. The heterodimers do not activate the NODAL receptor. LEFTY1 and LEFTY2 also bind CRIPTO and CRYPTIC coreceptors and prevent them f...
  • Signaling by NODAL, organism-specific biosystem (from REACTOME)
    Signaling by NODAL, organism-specific biosystemSignaling by NODAL is essential for patterning of the axes of the embryo and formation of mesoderm and endoderm (reviewed in Schier 2009, Shen 2007). The NODAL proprotein is secreted and cleaved extr...

General gene information

Markers

Other Names

  • Teratocarcinoma-derived growth factor-2
  • teratocarcinoma-derived growth factor 2 (retroposin, possibly expressed)
  • teratocarcinoma-derived growth factor 3, pseudogene

Gene Ontology Provided by GOA

Function Evidence Code Pubs
activin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
growth factor activity NAS
Non-traceable Author Statement
more info
PubMed 
nodal binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
BMP signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
anatomical structure development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
anterior/posterior pattern specification IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
determination of left/right symmetry IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
heart development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nodal signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_002718.2 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC000113
    Related
    ENST00000602699.1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    110520312..110523021
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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