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TDGF1P3 teratocarcinoma-derived growth factor 1 pseudogene 3 [ Homo sapiens (human) ]

Gene ID: 6998, updated on 26-Oct-2022

Summary

Official Symbol
TDGF1P3provided by HGNC
Official Full Name
teratocarcinoma-derived growth factor 1 pseudogene 3provided by HGNC
Primary source
HGNC:HGNC:11703
See related
Ensembl:ENSG00000225366 AllianceGenome:HGNC:11703
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CR-3; TDGF2; TDGF3; CRIPTO; CRIPTO3; CRIPTO-3
Summary
The TDGF3 locus has characteristics of a retrotransposon, including lack of introns and a poly(A) sequence. [provided by RefSeq, Jul 2008]
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Genomic context

See TDGF1P3 in Genome Data Viewer
Location:
Xq23
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) X NC_000023.11 (110520896..110523021)
110 current T2T-CHM13v2.0 (GCF_009914755.1) X NC_060947.1 (108968800..108970925)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (109764124..109766249)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene AMMECR nuclear protein 1 Neighboring gene G protein subunit gamma 5B Neighboring gene retrotransposon Gag like 9 Neighboring gene M6PR pseudogene 1 Neighboring gene chordin like 1

Genomic regions, transcripts, and products

General gene information

Markers

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables activin receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables growth factor activity NAS
Non-traceable Author Statement
more info
PubMed 
enables nodal binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables signaling receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in anatomical structure development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in anterior/posterior pattern specification IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in blood vessel development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in determination of left/right symmetry IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in heart development IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in nodal signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in signal transduction IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in cell surface IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
putative teratocarcinoma-derived growth factor 3
Names
Teratocarcinoma-derived growth factor-2
cripto-3 growth factor
epidermal growth factor-like cripto protein CR3
teratocarcinoma-derived growth factor 2 (retroposin, possibly expressed)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001397362.1NP_001384291.1  putative teratocarcinoma-derived growth factor 3

    Status: VALIDATED

    Source sequence(s)
    AC000113
    Consensus CDS
    CCDS94651.1
    UniProtKB/Swiss-Prot
    P51864
    Related
    ENSP00000507999.1, ENST00000602699.2
    Conserved Domains (2) summary
    pfam09443
    Location:115149
    CFC; Cripto_Frl-1_Cryptic (CFC)
    cl17037
    Location:147183
    NBD_sugar-kinase_HSP70_actin; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p14 Primary Assembly

    Range
    110520896..110523021
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060947.1 Alternate T2T-CHM13v2.0

    Range
    108968800..108970925
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)