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Mrto4 mRNA turnover 4, ribosome maturation factor [ Mus musculus (house mouse) ]

Gene ID: 69902, updated on 5-Aug-2018

Summary

Official Symbol
Mrto4provided by MGI
Official Full Name
mRNA turnover 4, ribosome maturation factorprovided by MGI
Primary source
MGI:MGI:1917152
See related
Ensembl:ENSMUSG00000028741 Vega:OTTMUSG00000009954
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mrt4; Mg684; 2610012O22Rik
Expression
Ubiquitous expression in CNS E11.5 (RPKM 24.0), liver E14 (RPKM 24.0) and 28 other tissues See more
Orthologs

Genomic context

See Mrto4 in Genome Data Viewer
Location:
4; 4 D3
Exon count:
8
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (139347440..139352576, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (138903360..138908213, complement)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene PQ loop repeat containing 2 Neighboring gene aldo-keto reductase family 7, member A5 (aflatoxin aldehyde reductase) Neighboring gene cyclin D3, pseudogene Neighboring gene ER membrane protein complex subunit 1 Neighboring gene ubiquitin protein ligase E3 component n-recognin 4 Neighboring gene nuclear encoded tRNA valine 1 (anticodon AAC)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
nuclear-transcribed mRNA catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
rRNA processing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ribosomal large subunit assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
intracellular IEA
Inferred from Electronic Annotation
more info
 
nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
mRNA turnover protein 4 homolog
Names
MRT4, mRNA turnover 4, homolog
mRNA turnover 4, homolog
muscle protein684
ribosome assembly factor Mrto4

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001290810.1NP_001277739.1  mRNA turnover protein 4 homolog isoform 1

    See identical proteins and their annotated locations for NP_001277739.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AK011387, BC096556, BY083288, BY246960
    Consensus CDS
    CCDS71505.1
    UniProtKB/Swiss-Prot
    Q9D0I8
    UniProtKB/TrEMBL
    A2AMU9
    Related
    ENSMUSP00000099561.3, OTTMUSP00000010544, ENSMUST00000102503.9, OTTMUST00000023116
    Conserved Domains (1) summary
    cd05796
    Location:21183
    Ribosomal_P0_like; Ribosomal protein L10 family, P0-like protein subfamily; composed of uncharacterized eukaryotic proteins with similarity to the 60S ribosomal protein P0, including the Saccharomyces cerevisiae protein called mRNA turnover protein 4 (MRT4). MRT4 may be ...
  2. NM_001356476.1NP_001343405.1  mRNA turnover protein 4 homolog isoform 3

    Status: VALIDATED

    Source sequence(s)
    AK011387, AL807811, BC096556, BY083288, BY246960
    Conserved Domains (1) summary
    cd05796
    Location:1136
    Ribosomal_P0_like; Ribosomal protein L10 family, P0-like protein subfamily; composed of uncharacterized eukaryotic proteins with similarity to the 60S ribosomal protein P0, including the Saccharomyces cerevisiae protein called mRNA turnover protein 4 (MRT4). MRT4 may be ...
  3. NM_023536.3NP_076025.1  mRNA turnover protein 4 homolog isoform 2

    See identical proteins and their annotated locations for NP_076025.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. It encodes isoform 2, which is shorter by an amino acid, compared to isoform 1.
    Source sequence(s)
    AK011387, BC096556, BY083288, BY246960
    Consensus CDS
    CCDS18845.1
    UniProtKB/Swiss-Prot
    Q9D0I8
    UniProtKB/TrEMBL
    A2AMV1
    Related
    ENSMUSP00000030513.6, OTTMUSP00000010545, ENSMUST00000030513.12, OTTMUST00000023117
    Conserved Domains (1) summary
    cd05796
    Location:21183
    Ribosomal_P0_like; Ribosomal protein L10 family, P0-like protein subfamily; composed of uncharacterized eukaryotic proteins with similarity to the 60S ribosomal protein P0, including the Saccharomyces cerevisiae protein called mRNA turnover protein 4 (MRT4). MRT4 may be ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

    Range
    139347440..139352576 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006539162.2XP_006539225.1  mRNA turnover protein 4 homolog isoform X1

    Conserved Domains (1) summary
    cd05796
    Location:1136
    Ribosomal_P0_like; Ribosomal protein L10 family, P0-like protein subfamily; composed of uncharacterized eukaryotic proteins with similarity to the 60S ribosomal protein P0, including the Saccharomyces cerevisiae protein called mRNA turnover protein 4 (MRT4). MRT4 may be ...
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