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TCTA T cell leukemia translocation altered [ Homo sapiens (human) ]

Gene ID: 6988, updated on 11-Jun-2021

Summary

Official Symbol
TCTAprovided by HGNC
Official Full Name
T cell leukemia translocation alteredprovided by HGNC
Primary source
HGNC:HGNC:11692
See related
Ensembl:ENSG00000145022 MIM:600690
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in thyroid (RPKM 27.1), kidney (RPKM 21.0) and 25 other tissues See more
Orthologs
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Genomic context

See TCTA in Genome Data Viewer
Location:
3p21.31
Exon count:
3
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (49412423..49416476)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (49449639..49453909)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene ras homolog family member A Neighboring gene Sharpr-MPRA regulatory region 7935 Neighboring gene aminomethyltransferase Neighboring gene nicolin 1 Neighboring gene RNA, 5S ribosomal pseudogene 130

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in negative regulation of osteoclast differentiation IDA
Inferred from Direct Assay
more info
PubMed 
involved_in osteoclast fusion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in osteoclast fusion IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
T-cell leukemia translocation-altered gene protein
Names
T-cell leukemia translocation-associated gene protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022171.3NP_071503.1  T-cell leukemia translocation-altered gene protein

    See identical proteins and their annotated locations for NP_071503.1

    Status: VALIDATED

    Source sequence(s)
    AC104452
    Consensus CDS
    CCDS2796.1
    UniProtKB/Swiss-Prot
    P57738
    Related
    ENSP00000273590.3, ENST00000273590.3
    Conserved Domains (1) summary
    pfam15128
    Location:18103
    T_cell_tran_alt; T-cell leukemia translocation-altered

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    49412423..49416476
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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