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Lyg1 lysozyme G-like 1 [ Mus musculus (house mouse) ]

Gene ID: 69541, updated on 8-Feb-2024

Summary

Official Symbol
Lyg1provided by MGI
Official Full Name
lysozyme G-like 1provided by MGI
Primary source
MGI:MGI:1916791
See related
Ensembl:ENSMUSG00000026085 AllianceGenome:MGI:1916791
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2300002O18Rik
Summary
Predicted to enable lysozyme activity. Predicted to be involved in defense response to Gram-positive bacterium. Predicted to be active in extracellular region. Orthologous to human LYG1 (lysozyme g1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in stomach adult (RPKM 4.2) and lung adult (RPKM 1.3) See more
Orthologs
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Genomic context

See Lyg1 in Genome Data Viewer
Location:
1 B; 1 16.29 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (37985819..37996840, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (37946738..37957759, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L30 Neighboring gene lysozyme G-like 2 Neighboring gene STARR-seq mESC enhancer starr_00687 Neighboring gene thioredoxin domain containing 9 Neighboring gene STARR-positive B cell enhancer ABC_E3269 Neighboring gene STARR-positive B cell enhancer ABC_E10006 Neighboring gene eukaryotic translation initiation factor 5B Neighboring gene STARR-seq mESC enhancer starr_00688 Neighboring gene predicted gene, 34448

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (1) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
enables hydrolase activity, acting on glycosyl bonds IEA
Inferred from Electronic Annotation
more info
 
enables lysozyme activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables lysozyme activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in defense response to Gram-positive bacterium IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in peptidoglycan catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027111.3NP_081387.1  lysozyme g-like protein 1 precursor

    See identical proteins and their annotated locations for NP_081387.1

    Status: PROVISIONAL

    Source sequence(s)
    AK009014
    Consensus CDS
    CCDS35543.1
    UniProtKB/Swiss-Prot
    Q9D7Q0
    UniProtKB/TrEMBL
    F8WIW2, Q0VE18
    Related
    ENSMUSP00000110544.2, ENSMUST00000114894.2
    Conserved Domains (1) summary
    cl00222
    Location:38195
    lysozyme_like; lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    37985819..37996840 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006496258.1XP_006496321.1  lysozyme g-like protein 1 isoform X1

    UniProtKB/TrEMBL
    F8WIW2
    Conserved Domains (1) summary
    cl00222
    Location:38158
    Lyz-like; lysozyme-like domains