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LYG1 lysozyme g1 [ Homo sapiens (human) ]

Gene ID: 129530, updated on 23-Nov-2021

Summary

Official Symbol
LYG1provided by HGNC
Official Full Name
lysozyme g1provided by HGNC
Primary source
HGNC:HGNC:27014
See related
Ensembl:ENSG00000144214
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LYGA1; SALW1939
Expression
Biased expression in kidney (RPKM 2.5), testis (RPKM 0.7) and 11 other tissues See more
Orthologs
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Genomic context

See LYG1 in Genome Data Viewer
Location:
2q11.2
Exon count:
11
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (99284238..99304775, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (99900701..99921238, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L30 Neighboring gene lysozyme g2 Neighboring gene uncharacterized LOC107985923 Neighboring gene thioredoxin domain containing 9 Neighboring gene eukaryotic translation initiation factor 5B Neighboring gene REV1 DNA directed polymerase

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

Associated conditions

Description Tests
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
GeneReviews: Not available

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables lysozyme activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell wall macromolecule catabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in defense response to Gram-positive bacterium IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in peptidoglycan catabolic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in extracellular region IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
lysozyme g-like protein 1
Names
lysozyme G-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001371380.1NP_001358309.1  lysozyme g-like protein 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AC079447
    Related
    ENSP00000386923.1, ENST00000409448.1
    Conserved Domains (1) summary
    cd16888
    Location:38194
    lyz_G-like_1; lysozyme G-like protein 1
  2. NM_174898.3NP_777558.1  lysozyme g-like protein 1 precursor

    See identical proteins and their annotated locations for NP_777558.1

    Status: VALIDATED

    Source sequence(s)
    AC079447, BC029126, BG194505
    Consensus CDS
    CCDS2043.1
    UniProtKB/Swiss-Prot
    Q8N1E2
    Related
    ENSP00000311320.4, ENST00000308528.9
    Conserved Domains (1) summary
    cd16888
    Location:38194
    lyz_G-like_1; lysozyme G-like protein 1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    99284238..99304775 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005263870.3XP_005263927.1  lysozyme g-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005263927.1

    UniProtKB/Swiss-Prot
    Q8N1E2
    Conserved Domains (1) summary
    cd16888
    Location:38194
    lyz_G-like_1; lysozyme G-like protein 1
  2. XM_011510580.2XP_011508882.1  lysozyme g-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011508882.1

    UniProtKB/Swiss-Prot
    Q8N1E2
    Conserved Domains (1) summary
    cd16888
    Location:38194
    lyz_G-like_1; lysozyme G-like protein 1
  3. XM_005263871.4XP_005263928.1  lysozyme g-like protein 1 isoform X1

    See identical proteins and their annotated locations for XP_005263928.1

    UniProtKB/Swiss-Prot
    Q8N1E2
    Conserved Domains (1) summary
    cd16888
    Location:38194
    lyz_G-like_1; lysozyme G-like protein 1
  4. XM_017003313.1XP_016858802.1  lysozyme g-like protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q8N1E2
    Conserved Domains (1) summary
    cd16888
    Location:38194
    lyz_G-like_1; lysozyme G-like protein 1
  5. XM_017003311.1XP_016858800.1  lysozyme g-like protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q8N1E2
    Conserved Domains (1) summary
    cd16888
    Location:38194
    lyz_G-like_1; lysozyme G-like protein 1
  6. XM_017003312.1XP_016858801.1  lysozyme g-like protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q8N1E2
    Conserved Domains (1) summary
    cd16888
    Location:38194
    lyz_G-like_1; lysozyme G-like protein 1
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