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MSMP microseminoprotein, prostate associated [ Homo sapiens (human) ]

Gene ID: 692094, updated on 5-Jan-2022

Summary

Official Symbol
MSMPprovided by HGNC
Official Full Name
microseminoprotein, prostate associatedprovided by HGNC
Primary source
HGNC:HGNC:29663
See related
Ensembl:ENSG00000215183 MIM:612191
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PSMP
Summary
This gene encodes a member of the beta-microseminoprotein family. Members of this protein family contain ten conserved cysteine residues that form intra-molecular disulfide bonds. The encoded protein may play a role in prostate cancer tumorigenesis. [provided by RefSeq, Jan 2011]
Expression
Ubiquitous expression in thyroid (RPKM 19.8), colon (RPKM 16.5) and 25 other tissues See more
Orthologs
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Genomic context

See MSMP in Genome Data Viewer
Location:
9p13.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 9 NC_000009.12 (35752990..35754276, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (35752987..35754273, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene microRNA 6853 Neighboring gene cAMP responsive element binding protein 3 Neighboring gene glucosylceramidase beta 2 Neighboring gene RGP1 homolog, RAB6A GEF complex partner 1 Neighboring gene natriuretic peptide receptor 2 Neighboring gene sperm associated antigen 8 Neighboring gene histidine triad nucleotide binding protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables CCR2 chemokine receptor binding IDA
Inferred from Direct Assay
more info
PubMed 
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 
involved_in lymphocyte chemotaxis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in monocyte chemotaxis IDA
Inferred from Direct Assay
more info
PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in extracellular space IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
prostate-associated microseminoprotein
Names
PC3 prostate cancer cell-secreted microprotein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044264.3NP_001037729.1  prostate-associated microseminoprotein precursor

    See identical proteins and their annotated locations for NP_001037729.1

    Status: REVIEWED

    Source sequence(s)
    BC071800, BE439525, DQ012170
    Consensus CDS
    CCDS43797.1
    UniProtKB/Swiss-Prot
    Q1L6U9
    Related
    ENSP00000419194.1, ENST00000436428.3
    Conserved Domains (1) summary
    pfam05825
    Location:55114
    PSP94; Beta-microseminoprotein (PSP-94)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p13 Primary Assembly

    Range
    35752990..35754276 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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