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Msmp microseminoprotein, prostate associated [ Mus musculus (house mouse) ]

Gene ID: 100039672, updated on 27-Nov-2024

Summary

Official Symbol
Msmpprovided by MGI
Official Full Name
microseminoprotein, prostate associatedprovided by MGI
Primary source
MGI:MGI:3652339
See related
Ensembl:ENSMUSG00000078719 AllianceGenome:MGI:3652339
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Psmp
Summary
Predicted to enable CCR2 chemokine receptor binding activity. Predicted to be involved in lymphocyte chemotaxis and monocyte chemotaxis. Predicted to be active in cytoplasm and extracellular space. Is expressed in femur; humerus; radius; tibia; and ulna. Orthologous to human MSMP (microseminoprotein, prostate associated). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in ovary adult (RPKM 29.8), thymus adult (RPKM 27.2) and 28 other tissues See more
Orthologs
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Genomic context

See Msmp in Genome Data Viewer
Location:
4 A5; 4 23.05 cM
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (43583216..43584494, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (43583216..43584494, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene talin 1 Neighboring gene STARR-seq mESC enhancer starr_10056 Neighboring gene cAMP responsive element binding protein 3 Neighboring gene glucosidase beta 2 Neighboring gene RAB6A GEF compex partner 1 Neighboring gene STARR-seq mESC enhancer starr_10057 Neighboring gene predicted gene 12472 Neighboring gene predicted gene, 42279

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables CCR2 chemokine receptor binding ISO
Inferred from Sequence Orthology
more info
 
enables CCR2 chemokine receptor binding ISS
Inferred from Sequence or Structural Similarity
more info
 
enables cytokine activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 
involved_in lymphocyte chemotaxis ISO
Inferred from Sequence Orthology
more info
 
involved_in lymphocyte chemotaxis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in monocyte chemotaxis ISO
Inferred from Sequence Orthology
more info
 
involved_in monocyte chemotaxis ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular space ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular space ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
prostate-associated microseminoprotein
Names
PC3-secreted microprotein homolog
Vmicroseminoprotein, prostate associated

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099314.1NP_001092784.1  prostate-associated microseminoprotein precursor

    See identical proteins and their annotated locations for NP_001092784.1

    Status: VALIDATED

    Source sequence(s)
    AL732626
    Consensus CDS
    CCDS51167.1
    UniProtKB/Swiss-Prot
    B1AWI6
    Related
    ENSMUSP00000103516.3, ENSMUST00000107884.3
    Conserved Domains (1) summary
    pfam05825
    Location:55114
    PSP94; Beta-microseminoprotein (PSP-94)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    43583216..43584494 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)