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Cab39l calcium binding protein 39-like [ Mus musculus (house mouse) ]

Gene ID: 69008, updated on 2-Nov-2024

Summary

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Official Symbol
Cab39lprovided by MGI
Official Full Name
calcium binding protein 39-likeprovided by MGI
Primary source
MGI:MGI:1914081
See related
Ensembl:ENSMUSG00000021981 AllianceGenome:MGI:1914081
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MO2L; 1500031K13Rik; 2810425O13Rik; 4930520C08Rik
Summary
Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in intracellular signal transduction. Is expressed in several structures, including alimentary system; cardiovascular system; eye; genitourinary system; and nervous system. Orthologous to human CAB39L (calcium binding protein 39 like). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in bladder adult (RPKM 15.1), testis adult (RPKM 7.4) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Cab39l in Genome Data Viewer
Location:
14 C3; 14 31.48 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (59678400..59786353)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (59440934..59548904)

Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 45935 Neighboring gene PHD finger protein 11C Neighboring gene SET domain, bifurcated 2 Neighboring gene STARR-positive B cell enhancer ABC_E4112 Neighboring gene cytidine and dCMP deaminase domain containing 1 Neighboring gene aldo-keto reductase family 1, member B8 pseudogene Neighboring gene STARR-seq mESC enhancer starr_36842 Neighboring gene ribosomal protein S9 pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Loss of LPAR6 and CAB39L dysregulates the basal-to-luminal urothelial differentiation program, contributing to bladder carcinogenesis. Lee S, et al. Cell Rep, 2024 May 28. PMID 38676926, Free PMC Article
  2. Molecular Characterization of the Genital Organizer: Gene Expression Profile of the Mouse Urethral Plate Epithelium. Armfield BA, et al. J Urol, 2016 Oct. PMID 27173853, Free PMC Article
  3. The protein interactome of collapsin response mediator protein-2 (CRMP2/DPYSL2) reveals novel partner proteins in brain tissue. Martins-de-Souza D, et al. Proteomics Clin Appl, 2015 Oct. PMID 25921334
  4. Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set. VanBuren V, et al. Genome Res, 2002 Dec. PMID 12466305, Free PMC Article
  5. Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. Carninci P, et al. Genome Res, 2003 Jun. PMID 12819125, Free PMC Article

See all (29) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 
  • Targeted (4)  1 citation

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein serine/threonine kinase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in intracellular signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
calcium-binding protein 39-like
Names
MO25beta
mo25-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001360591.1 → NP_001347520.1  calcium-binding protein 39-like

    Status: VALIDATED

    Source sequence(s)
    AK030474, AK053642, AW122324, BQ562937, BY789575
    Consensus CDS
    CCDS27171.1
    UniProtKB/Swiss-Prot
    Q8BG52, Q91WB8, Q91YL0, Q9DB16
    Conserved Domains (1) summary
    pfam08569
    Location:6 → 333
    Mo25; Mo25-like

  2. NM_001360592.1 → NP_001347521.1  calcium-binding protein 39-like

    Status: VALIDATED

    Source sequence(s)
    AK030474, AK053642, AK076867, AW122324, BY789575
    Consensus CDS
    CCDS27171.1
    UniProtKB/Swiss-Prot
    Q8BG52, Q91WB8, Q91YL0, Q9DB16
    Conserved Domains (1) summary
    pfam08569
    Location:6 → 333
    Mo25; Mo25-like

  3. NM_001360593.1 → NP_001347522.1  calcium-binding protein 39-like

    Status: VALIDATED

    Source sequence(s)
    AK030474, AK053642, AW122324, CX563320
    Consensus CDS
    CCDS27171.1
    UniProtKB/Swiss-Prot
    Q8BG52, Q91WB8, Q91YL0, Q9DB16
    Conserved Domains (1) summary
    pfam08569
    Location:6 → 333
    Mo25; Mo25-like

  4. NM_026908.4 → NP_081184.3  calcium-binding protein 39-like

    See identical proteins and their annotated locations for NP_081184.3

    Status: VALIDATED

    Source sequence(s)
    AK030474, AK053642, AW122324, BY789575
    Consensus CDS
    CCDS27171.1
    UniProtKB/Swiss-Prot
    Q8BG52, Q91WB8, Q91YL0, Q9DB16
    Related
    ENSMUSP00000022553.6, ENSMUST00000022553.6
    Conserved Domains (1) summary
    pfam08569
    Location:6 → 333
    Mo25; Mo25-like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000080.7 Reference GRCm39 C57BL/6J

    Range
    59678400..59786353
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036158837.1 → XP_036014730.1  calcium-binding protein 39-like isoform X1

    UniProtKB/Swiss-Prot
    Q8BG52, Q91WB8, Q91YL0, Q9DB16
    Conserved Domains (1) summary
    pfam08569
    Location:6 → 333
    Mo25; Mo25-like

  2. XM_036158838.1 → XP_036014731.1  calcium-binding protein 39-like isoform X1

    UniProtKB/Swiss-Prot
    Q8BG52, Q91WB8, Q91YL0, Q9DB16
    Conserved Domains (1) summary
    pfam08569
    Location:6 → 333
    Mo25; Mo25-like

  3. XM_017316177.3 → XP_017171666.1  calcium-binding protein 39-like isoform X2

    Conserved Domains (1) summary
    pfam08569
    Location:6 → 313
    Mo25; Mo25-like
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9DB16.3 GenPept UniProtKB/Swiss-Prot:Q9DB16

Gene LinkOut

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