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Tyw5 tRNA-yW synthesizing protein 5 [ Mus musculus (house mouse) ]

Gene ID: 68736, updated on 31-Jan-2019

Summary

Official Symbol
Tyw5provided by MGI
Official Full Name
tRNA-yW synthesizing protein 5provided by MGI
Primary source
MGI:MGI:1915986
See related
Ensembl:ENSMUSG00000048495
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110034B05Rik
Expression
Ubiquitous expression in bladder adult (RPKM 4.4), placenta adult (RPKM 4.0) and 27 other tissues See more
Orthologs

Genomic context

See Tyw5 in Genome Data Viewer
Location:
1; 1 C1.3
Exon count:
9
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (57388235..57406674, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (57445088..57463518, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930558J18 gene Neighboring gene RIKEN cDNA 1700066M21 gene Neighboring gene matrix AAA peptidase interacting protein 1 Neighboring gene ribosomal protein L6 pseudogene Neighboring gene spermine synthase pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Homology

Clone Names

  • FLJ37953, MGC117744

Gene Ontology Provided by MGI

Process Evidence Code Pubs
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
tRNA processing IEA
Inferred from Electronic Annotation
more info
 
wybutosine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
wybutosine biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
tRNA wybutosine-synthesizing protein 5
Names
jmjC domain-containing protein C2orf60 homolog
tRNA yW-synthesizing enzyme 5
tRNA(Phe) (7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase
NP_001032831.2
NP_001289891.1
NP_001289892.1
NP_001289893.1
XP_011236888.1
XP_011236889.1
XP_017177819.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037742.2NP_001032831.2  tRNA wybutosine-synthesizing protein 5 isoform 1

    See identical proteins and their annotated locations for NP_001032831.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) uses an alternate in-frame splice site and lacks an alternate in-frame exon in the 5' coding region, compared to variant 4. The resulting protein (isoform 1) is shorter than isoform 4.
    Source sequence(s)
    AC161493, BC099495, BC132289, BU697704
    Consensus CDS
    CCDS14966.2
    UniProtKB/Swiss-Prot
    A2RSX7
    Related
    ENSMUSP00000125427.1, ENSMUST00000162686.7
    Conserved Domains (1) summary
    pfam13621
    Location:17255
    Cupin_8; Cupin-like domain
  2. NM_001302962.1NP_001289891.1  tRNA wybutosine-synthesizing protein 5 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) encodes the longest isoform (4).
    Source sequence(s)
    AC161493, BC099495, BC144765, BU697704, CF951173
    Related
    ENSMUSP00000128576.1, ENSMUST00000160837.7
    Conserved Domains (1) summary
    pfam13621
    Location:17257
    Cupin_8; Cupin-like domain
  3. NM_001302963.1NP_001289892.1  tRNA wybutosine-synthesizing protein 5 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks an alternate internal exon, uses an alternate in-frame splice site in the 5' coding region, and uses an in-frame downstream start codon compared to variant 4. The resulting protein (isoform 5) is shorter than isoform 4.
    Source sequence(s)
    AC161493, BC099495, BC144765
    Conserved Domains (1) summary
    cl21464
    Location:13115
    cupin_like; Conserved domain found in cupin and related proteins
  4. NM_001302964.1NP_001289893.1  tRNA wybutosine-synthesizing protein 5 isoform 3

    See identical proteins and their annotated locations for NP_001289893.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate internal exon and uses an in-frame downstream start codon compared to variant 4. The resulting protein (isoform 3) has a shorter N-terminus than isoform 4.
    Source sequence(s)
    AC161493, BC099495, BC144766
    Conserved Domains (1) summary
    cl21464
    Location:13120
    cupin_like; Conserved domain found in cupin and related proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

    Range
    57388235..57406674 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017322330.1XP_017177819.1  tRNA wybutosine-synthesizing protein 5 isoform X1

  2. XM_011238587.2XP_011236889.1  tRNA wybutosine-synthesizing protein 5 isoform X2

    See identical proteins and their annotated locations for XP_011236889.1

    Conserved Domains (1) summary
    cl21464
    Location:13120
    cupin_like; Conserved domain found in cupin and related proteins
  3. XM_011238586.2XP_011236888.1  tRNA wybutosine-synthesizing protein 5 isoform X2

    See identical proteins and their annotated locations for XP_011236888.1

    Conserved Domains (1) summary
    cl21464
    Location:13120
    cupin_like; Conserved domain found in cupin and related proteins

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001114102.1: Suppressed sequence

    Description
    NM_001114102.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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