U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Nufip2 nuclear FMR1 interacting protein 2 [ Mus musculus (house mouse) ]

Gene ID: 68564, updated on 8-Jan-2023

Summary

Official Symbol
Nufip2provided by MGI
Official Full Name
nuclear FMR1 interacting protein 2provided by MGI
Primary source
MGI:MGI:1915814
See related
Ensembl:ENSMUSG00000037857 AllianceGenome:MGI:1915814
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PIG1; mKIAA1321; 1110001M19Rik; 9530056D24Rik
Summary
Predicted to enable RNA binding activity. Predicted to be located in cytosol and nuclear body. Predicted to be active in cytoplasmic stress granule; nucleoplasm; and polysomal ribosome. Orthologous to human NUFIP2 (nuclear FMR1 interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 5.5), bladder adult (RPKM 4.9) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Nufip2 in Genome Data Viewer
Location:
11; 11 B5
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (77576566..77608792)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (77685764..77717966)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ribosomal protein S2 pseudogene Neighboring gene predicted gene, 23132 Neighboring gene crystallin, beta A1 Neighboring gene 60S ribosomal protein L15 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables RNA binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasmic stress granule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasmic stress granule ISO
Inferred from Sequence Orthology
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 
is_active_in polysomal ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in polysomal ribosome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
FMR1-interacting protein NUFIP2; nuclear fragile X mental retardation-interacting protein 2
Names
82 kDa FMRP-interacting protein
82-FIP
FMRP-interacting protein 2
proliferation-inducing gene 1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024205.2NP_001019376.1  FMR1-interacting protein NUFIP2

    See identical proteins and their annotated locations for NP_001019376.1

    Status: VALIDATED

    Source sequence(s)
    AL591136
    Consensus CDS
    CCDS25083.1
    UniProtKB/Swiss-Prot
    Q5F2E7, Q80TF1
    Related
    ENSMUSP00000098365.5, ENSMUST00000100802.11
    Conserved Domains (1) summary
    pfam15293
    Location:90685
    NUFIP2; Nuclear fragile X mental retardation-interacting protein 2

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    77576566..77608792
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006534062.5XP_006534125.1  nuclear fragile X mental retardation-interacting protein 2 isoform X2

    See identical proteins and their annotated locations for XP_006534125.1

    UniProtKB/Swiss-Prot
    Q5F2E7, Q80TF1
    Conserved Domains (1) summary
    pfam15293
    Location:90685
    NUFIP2; Nuclear fragile X mental retardation-interacting protein 2
  2. XM_036156930.1XP_036012823.1  nuclear fragile X mental retardation-interacting protein 2 isoform X1

    Conserved Domains (1) summary
    pfam15293
    Location:108700
    NUFIP2; Nuclear fragile X mental retardation-interacting protein 2
  3. XM_006534063.5XP_006534126.1  nuclear fragile X mental retardation-interacting protein 2 isoform X3

    See identical proteins and their annotated locations for XP_006534126.1

    Conserved Domains (1) summary
    pfam15293
    Location:1525
    NUFIP2; Nuclear fragile X mental retardation-interacting protein 2