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Wipf2 WAS/WASL interacting protein family, member 2 [ Mus musculus (house mouse) ]

Gene ID: 68524, updated on 5-Mar-2024

Summary

Official Symbol
Wipf2provided by MGI
Official Full Name
WAS/WASL interacting protein family, member 2provided by MGI
Primary source
MGI:MGI:1924462
See related
Ensembl:ENSMUSG00000038013 AllianceGenome:MGI:1924462
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Wich; Wire; Gm1176; 1110014J05Rik; 5730509C05Rik
Summary
Predicted to enable actin binding activity. Predicted to be involved in actin filament-based movement. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be active in actin filament. Orthologous to human WIPF2 (WAS/WASL interacting protein family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 5.6), cortex adult (RPKM 4.8) and 28 other tissues See more
Orthologs
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Genomic context

See Wipf2 in Genome Data Viewer
Location:
11 D; 11 62.71 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (98754424..98796404)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (98863598..98905578)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E5276 Neighboring gene predicted gene 12359 Neighboring gene exon junction complex subunit Neighboring gene Rap guanine nucleotide exchange factor (GEF)-like 1 Neighboring gene STARR-positive B cell enhancer ABC_E9145 Neighboring gene VISTA enhancer mm1323 Neighboring gene STARR-positive B cell enhancer ABC_E203 Neighboring gene cell division cycle 6 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:98803426-98803613 Neighboring gene retinoic acid receptor, alpha Neighboring gene predicted gene, 46294

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
WAS/WASL-interacting protein family member 2
Names
WASP-binding protein
WASP-interacting protein-related protein
WIP-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_197940.2NP_922922.1  WAS/WASL-interacting protein family member 2

    See identical proteins and their annotated locations for NP_922922.1

    Status: VALIDATED

    Source sequence(s)
    AL591067
    Consensus CDS
    CCDS25366.1
    UniProtKB/Swiss-Prot
    Q6PEV3
    Related
    ENSMUSP00000046991.9, ENSMUST00000037480.9
    Conserved Domains (3) summary
    PRK12323
    Location:60220
    PRK12323; DNA polymerase III subunit gamma/tau
    cd21762
    Location:5053
    WH2; actin-binding sequence [structural motif]
    cl41728
    Location:3362
    WH2; Wiskott-Aldrich Syndrome Homology (WASP) region 2 (WH2 motif), and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    98754424..98796404
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)