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Hsbp1 heat shock factor binding protein 1 [ Mus musculus (house mouse) ]

Gene ID: 68196, updated on 8-May-2024

Summary

Official Symbol
Hsbp1provided by MGI
Official Full Name
heat shock factor binding protein 1provided by MGI
Primary source
MGI:MGI:1915446
See related
Ensembl:ENSMUSG00000031839 AllianceGenome:MGI:1915446
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hsp25; 0610007A03Rik
Summary
Predicted to enable identical protein binding activity. Acts upstream of or within endodermal cell differentiation. Predicted to be located in cytoskeleton. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including early embryo and ganglia. Orthologous to human HSBP1 (heat shock factor binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 226.9), CNS E18 (RPKM 192.9) and 26 other tissues See more
Orthologs
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Genomic context

See Hsbp1 in Genome Data Viewer
Location:
8 E1; 8 67.54 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (120071277..120075668)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (119344538..119348929)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene cadherin 13 Neighboring gene STARR-seq mESC enhancer starr_22840 Neighboring gene STARR-seq mESC enhancer starr_22841 Neighboring gene predicted gene, 22999 Neighboring gene STARR-seq mESC enhancer starr_22842 Neighboring gene STARR-seq mESC enhancer starr_22844 Neighboring gene predicted gene, 31893 Neighboring gene STARR-seq mESC enhancer starr_22846 Neighboring gene STARR-seq mESC enhancer starr_22847 Neighboring gene STARR-positive B cell enhancer ABC_E10525 Neighboring gene STARR-positive B cell enhancer ABC_E3809 Neighboring gene predicted gene 45723 Neighboring gene predicted gene, 32006 Neighboring gene malonyl-CoA decarboxylase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Targeted (1)  1 citation

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in axonal transport of mitochondrion ISO
Inferred from Sequence Orthology
more info
 
involved_in cellular heat acclimation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within endodermal cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in muscle contraction ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
heat shock factor-binding protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024219.1NP_077181.1  heat shock factor-binding protein 1

    See identical proteins and their annotated locations for NP_077181.1

    Status: VALIDATED

    Source sequence(s)
    BC002153
    Consensus CDS
    CCDS40492.1
    UniProtKB/Swiss-Prot
    Q3UKN1, Q9CQZ1
    Related
    ENSMUSP00000034300.7, ENSMUST00000034300.8
    Conserved Domains (1) summary
    pfam06825
    Location:1060
    HSBP1; Heat shock factor binding protein 1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    120071277..120075668
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)