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Mphosph10 M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein) [ Mus musculus (house mouse) ]

Gene ID: 67973, updated on 30-Apr-2024

Summary

Official Symbol
Mphosph10provided by MGI
Official Full Name
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)provided by MGI
Primary source
MGI:MGI:1915223
See related
Ensembl:ENSMUSG00000030521 AllianceGenome:MGI:1915223
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2810453H10Rik; 5730405D16Rik
Summary
Predicted to act upstream of or within rRNA processing. Predicted to be located in chromosome and nucleolus. Predicted to be part of Mpp10 complex and small-subunit processome. Is expressed in esophagus; lung; pituitary gland; urethra; and vertebral axis musculature. Orthologous to human MPHOSPH10 (M-phase phosphoprotein 10). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in CNS E11.5 (RPKM 16.9), liver E14 (RPKM 10.4) and 11 other tissues See more
Orthologs
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Genomic context

See Mphosph10 in Genome Data Viewer
Location:
7 34.64 cM; 7 C
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (64026289..64041984, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (64376541..64392236, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_19037 Neighboring gene myotubularin related protein 10 Neighboring gene STARR-seq mESC enhancer starr_19038 Neighboring gene STARR-seq mESC enhancer starr_19039 Neighboring gene SET translocation pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:71537088-71537271 Neighboring gene STARR-positive B cell enhancer ABC_E4931 Neighboring gene FANCD2/FANCI-associated nuclease 1 Neighboring gene methylmalonyl CoA epimerase Neighboring gene amyloid beta precursor protein binding family A member 2 Neighboring gene STARR-seq mESC enhancer starr_19041 Neighboring gene STARR-seq mESC enhancer starr_19042

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within rRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in rRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of Mpp10 complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of Mpp10 complex ISO
Inferred from Sequence Orthology
more info
 
located_in chromosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
 
part_of sno(s)RNA-containing ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
U3 small nucleolar ribonucleoprotein protein MPP10
Names
m phase phosphoprotein 10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026483.2NP_080759.2  U3 small nucleolar ribonucleoprotein protein MPP10

    See identical proteins and their annotated locations for NP_080759.2

    Status: VALIDATED

    Source sequence(s)
    AK008785, AK017490, AV222458, CK390971
    Consensus CDS
    CCDS21333.1
    UniProtKB/Swiss-Prot
    E9QM78, Q810V0
    UniProtKB/TrEMBL
    A0PJ89
    Related
    ENSMUSP00000032735.6, ENSMUST00000032735.8
    Conserved Domains (1) summary
    pfam04006
    Location:22632
    Mpp10; Mpp10 protein

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    64026289..64041984 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)