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Fbxo28 F-box protein 28 [ Mus musculus (house mouse) ]

Gene ID: 67948, updated on 30-Apr-2024

Summary

Official Symbol
Fbxo28provided by MGI
Official Full Name
F-box protein 28provided by MGI
Primary source
MGI:MGI:1261890
See related
Ensembl:ENSMUSG00000047539 AllianceGenome:MGI:1261890
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fbx28; mKIAA0483; D1Ertd578e; 4833428J17Rik; 5730505P19Rik
Summary
Predicted to enable identical protein binding activity. Predicted to be involved in protein polyubiquitination. Predicted to be located in kinetochore. Orthologous to human FBXO28 (F-box protein 28). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in whole brain E14.5 (RPKM 7.0), CNS E14 (RPKM 6.8) and 28 other tissues See more
Orthologs
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Genomic context

See Fbxo28 in Genome Data Viewer
Location:
1 H5; 1 84.93 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (182140667..182169171, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (182313102..182341606, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene delta 4-desaturase, sphingolipid 1 Neighboring gene RIKEN cDNA 1700047M11 gene Neighboring gene STARR-seq mESC enhancer starr_03278 Neighboring gene STARR-positive B cell enhancer mm9_chr1:184271643-184271944 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E5879 Neighboring gene transformation related protein 53 binding protein 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • KIAA0483, MGC90899

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in protein polyubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
 
located_in kinetochore ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175127.2NP_780336.1  F-box only protein 28

    See identical proteins and their annotated locations for NP_780336.1

    Status: VALIDATED

    Source sequence(s)
    BC094542
    Consensus CDS
    CCDS15588.1
    UniProtKB/Swiss-Prot
    Q3TS97, Q7TMH9, Q8BIF6, Q8BIG4
    Related
    ENSMUSP00000054718.5, ENSMUST00000051431.10
    Conserved Domains (1) summary
    pfam00646
    Location:67108
    F-box; F-box domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    182140667..182169171 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)