Fbxo28 F-box protein 28 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Fbxo28provided by MGI
Official Full Name: F-box protein 28provided by MGI
Primary source: MGI:MGI:1261890
See related: Ensembl:ENSMUSG00000047539 AllianceGenome:MGI:1261890
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Fbx28; mKIAA0483; D1Ertd578e; 4833428J17Rik; 5730505P19Rik
Summary: Predicted to enable identical protein binding activity. Predicted to be involved in protein polyubiquitination. Predicted to be located in kinetochore. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 100. Orthologous to human FBXO28 (F-box protein 28). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Ubiquitous expression in whole brain E14.5 (RPKM 7.0), CNS E14 (RPKM 6.8) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 1 H5; 1 84.93 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	1	NC_000067.7 (182140667..182169171, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	1	NC_000067.6 (182313102..182341606, complement)

Chromosome 1 - NC_000067.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (3)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D1Ertd578e (e-PCR), detects polymorphism
- UniSTS:167281

RH130101 (e-PCR)
- UniSTS:213389

NoName (e-PCR)
- UniSTS:493258

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables identical protein binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in protein polyubiquitination	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in kinetochore	ISO Inferred from Sequence Orthology more info
located_in kinetochore	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: F-box only protein 28

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.