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Tprgl transformation related protein 63 regulated like [ Mus musculus (house mouse) ]

Gene ID: 67808, updated on 8-Nov-2022

Summary

Official Symbol
Tprglprovided by MGI
Official Full Name
transformation related protein 63 regulated likeprovided by MGI
Primary source
MGI:MGI:1915058
See related
Ensembl:ENSMUSG00000029030 AllianceGenome:MGI:1915058
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mover; Svap30; Tprg1l; 1200015A19Rik
Summary
Enables identical protein binding activity. Predicted to be involved in regulation of glutamatergic synaptic transmission. Predicted to be located in calyx of Held. Predicted to be active in synaptic vesicle. Is expressed in several structures, including gut; hemolymphoid system gland; male reproductive gland or organ; nervous system; and nose. Orthologous to human TPRG1L (tumor protein p63 regulated 1 like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 110.0), lung adult (RPKM 103.0) and 28 other tissues See more
Orthologs
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Genomic context

See Tprgl in Genome Data Viewer
Location:
4; 4 E2
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (154241942..154246763, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (154157485..154162306, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene transformation related protein 73 Neighboring gene predicted gene, 26036 Neighboring gene WD repeat containing, antisense to Trp73 Neighboring gene multiple EGF-like-domains 6 Neighboring gene 60S ribosomal protein L24 pseudogene Neighboring gene Rho guanine nucleotide exchange factor (GEF) 16 Neighboring gene predicted gene, 52687

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calmodulin binding IDA
Inferred from Direct Assay
more info
PubMed 
enables identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in calyx of Held ISO
Inferred from Sequence Orthology
more info
 
located_in calyx of Held ISO
Inferred from Sequence Orthology
more info
 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
is_active_in extrinsic component of synaptic vesicle membrane ISO
Inferred from Sequence Orthology
more info
 
is_active_in glutamatergic synapse ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in presynapse IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in presynapse IPI
Inferred from Physical Interaction
more info
PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 
is_active_in synaptic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in synaptic vesicle ISO
Inferred from Sequence Orthology
more info
 
located_in synaptic vesicle ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 

General protein information

Preferred Names
tumor protein p63-regulated gene 1-like protein
Names
mossy-fiber terminal-associated vertebrate-specific presynaptic protein
synaptic vesicle associated protein of 30 kD

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026388.2NP_080664.1  tumor protein p63-regulated gene 1-like protein

    See identical proteins and their annotated locations for NP_080664.1

    Status: VALIDATED

    Source sequence(s)
    AI840915, AK004324, AK004777, BY739996
    Consensus CDS
    CCDS19011.1
    UniProtKB/Swiss-Prot
    Q8BTC6, Q9DBS2
    Related
    ENSMUSP00000030896.9, ENSMUST00000030896.15
    Conserved Domains (1) summary
    pfam12456
    Location:61162
    hSac2; Inositol phosphatase

RNA

  1. NR_151647.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AI840915, AK004324, AK004777, AL806525, BY739996

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    154241942..154246763 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006539129.4XP_006539192.3  tumor protein p63-regulated gene 1-like protein isoform X1

    Conserved Domains (2) summary
    pfam12456
    Location:174264
    hSac2; Inositol phosphatase
    cl02324
    Location:93197
    DUF721; Protein of unknown function (DUF721)