U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Anp32b acidic nuclear phosphoprotein 32 family member B [ Mus musculus (house mouse) ]

Gene ID: 67628, updated on 16-Apr-2024

Summary

Official Symbol
Anp32bprovided by MGI
Official Full Name
acidic nuclear phosphoprotein 32 family member Bprovided by MGI
Primary source
MGI:MGI:1914878
See related
Ensembl:ENSMUSG00000028333 AllianceGenome:MGI:1914878
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PAL31; Ssp29; PHAPI2a; 2410015B15Rik
Summary
Predicted to enable RNA polymerase binding activity and histone binding activity. Acts upstream of or within several processes, including inner ear development; roof of mouth development; and ventricular system development. Located in nucleus. Is expressed in several structures, including eye; heart; and metanephros. Orthologous to human ANP32B (acidic nuclear phosphoprotein 32 family member B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in liver E14 (RPKM 62.7), liver E14.5 (RPKM 50.7) and 27 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
4 B1; 4 24.79 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (46450926..46472657)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (46450926..46472657)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_10125 Neighboring gene tRNA methyltransferase O Neighboring gene hemogen Neighboring gene STARR-positive B cell enhancer ABC_E9585 Neighboring gene STARR-positive B cell enhancer ABC_E3487 Neighboring gene predicted gene, 22247 Neighboring gene N-acetylneuraminic acid synthase (sialic acid synthase) Neighboring gene tripartite motif-containing 14 Neighboring gene STARR-positive B cell enhancer ABC_E3488 Neighboring gene predicted gene, 54223

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (4)  1 citation
  • Endonuclease-mediated (4) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • MGC103080

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA polymerase binding ISO
Inferred from Sequence Orthology
more info
 
enables histone binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables histone binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
PubMed 

General protein information

Preferred Names
acidic leucine-rich nuclear phosphoprotein 32 family member B
Names
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
acidic protein rich in leucines
proliferation related acidic leucine rich protein PAL31

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_130889.3NP_570959.1  acidic leucine-rich nuclear phosphoprotein 32 family member B

    See identical proteins and their annotated locations for NP_570959.1

    Status: VALIDATED

    Source sequence(s)
    AK165807, CJ053476, CK623910
    Consensus CDS
    CCDS18151.1
    UniProtKB/Swiss-Prot
    B1AVH9, Q566J4, Q9EST5
    Related
    ENSMUSP00000099990.5, ENSMUST00000102926.5
    Conserved Domains (3) summary
    COG4886
    Location:16115
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00035
    Location:90113
    LRR_NTF; leucine-rich repeat [structural motif]
    pfam14580
    Location:71146
    LRR_9; Leucine-rich repeat

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    46450926..46472657
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011250089.4XP_011248391.1  acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1

    Conserved Domains (2) summary
    sd00035
    Location:6184
    LRR_NTF; leucine-rich repeat [structural motif]
    pfam14580
    Location:42117
    LRR_9; Leucine-rich repeat