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BRDT bromodomain testis associated [ Homo sapiens (human) ]

Gene ID: 676, updated on 21-Dec-2019

Summary

Official Symbol
BRDTprovided by HGNC
Official Full Name
bromodomain testis associatedprovided by HGNC
Primary source
HGNC:HGNC:1105
See related
Ensembl:ENSG00000137948 MIM:602144
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT9; BRD6; SPGF21
Summary
BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Several transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
Expression
Restricted expression toward testis (RPKM 59.8) See more
Orthologs

Genomic context

See BRDT in Genome Data Viewer
Location:
1p22.1
Exon count:
21
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (91949371..92014428)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (92414928..92479985)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene transforming growth factor beta receptor 3 Neighboring gene Sharpr-MPRA regulatory region 4673 Neighboring gene RNA, 7SL, cytoplasmic 653, pseudogene Neighboring gene epoxide hydrolase 4 Neighboring gene lysophosphatidylcholine acyltransferase 2b, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Replication interactions

Interaction Pubs
Knockdown of bromodomain, testis-specific (BRDT) by siRNA inhibits HIV-1 replication in HeLa P4/R5 cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
histone binding IDA
Inferred from Direct Assay
more info
PubMed 
lysine-acetylated histone binding ISS
Inferred from Sequence or Structural Similarity
more info
 
transcription coactivator activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
RNA splicing IEA
Inferred from Electronic Annotation
more info
 
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
chromatin remodeling ISS
Inferred from Sequence or Structural Similarity
more info
 
histone displacement ISS
Inferred from Sequence or Structural Similarity
more info
 
mRNA processing IEA
Inferred from Electronic Annotation
more info
 
male meiosis I ISS
Inferred from Sequence or Structural Similarity
more info
 
male meiotic nuclear division ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transcription involved in meiotic cell cycle ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of RNA splicing ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of transcription, DNA-templated IMP
Inferred from Mutant Phenotype
more info
PubMed 
spermatogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
bromodomain testis-specific protein
Names
RING3-like protein
bromodomain, testis-specific
cancer/testis antigen 9

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001242805.2NP_001229734.2  bromodomain testis-specific protein isoform b

    See identical proteins and their annotated locations for NP_001229734.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 4. The resulting isoform (b) lacks a short internal segment compared to isoform a. Variants 1, 2, and 3 all encode the same isoform (b).
    Source sequence(s)
    AC114486, AK302758, AK303008, AY338951, BX648135
    Consensus CDS
    CCDS735.1
    UniProtKB/Swiss-Prot
    Q58F21
    Related
    ENSP00000354568.3, ENST00000362005.7
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:272373
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:509571
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:905947
    BRD4_CDT; C-terminal domain of bromodomain protein 4
  2. NM_001242806.2NP_001229735.2  bromodomain testis-specific protein isoform a

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) encodes the longest isoform (a).
    Source sequence(s)
    AC114486, AK302758, AK303008, AY338951, BX648135, DB072781
    Consensus CDS
    CCDS72820.1
    UniProtKB/Swiss-Prot
    Q58F21
    Related
    ENSP00000387822.2, ENST00000399546.6
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:276377
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:513575
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:909951
    BRD4_CDT; C-terminal domain of bromodomain protein 4
  3. NM_001242807.2NP_001229736.2  bromodomain testis-specific protein isoform c

    See identical proteins and their annotated locations for NP_001229736.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, lacks an alternate in-frame exon, and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 4. The resulting isoform (c) lacks two internal segments compared to isoform a. Variants 5 and 6 both encode the same protein.
    Source sequence(s)
    AK302758, AK316442, AY338951, BX648135, DC402057
    Consensus CDS
    CCDS55615.1
    UniProtKB/Swiss-Prot
    Q58F21
    Conserved Domains (4) summary
    cd05498
    Location:226327
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:463525
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:859901
    BRD4_CDT; C-terminal domain of bromodomain protein 4
    cl02556
    Location:2787
    Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
  4. NM_001242808.2NP_001229737.2  bromodomain testis-specific protein isoform c

    See identical proteins and their annotated locations for NP_001229737.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) lacks an alternate in-frame exon and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 4. The resulting isoform (c) lacks two internal segments compared to isoform a. Variants 5 and 6 both encode the same protein.
    Source sequence(s)
    AC114486, AK302758, AY338951, BX648135
    Consensus CDS
    CCDS55615.1
    UniProtKB/Swiss-Prot
    Q58F21
    Related
    ENSP00000378038.3, ENST00000394530.7
    Conserved Domains (4) summary
    cd05498
    Location:226327
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:463525
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:859901
    BRD4_CDT; C-terminal domain of bromodomain protein 4
    cl02556
    Location:2787
    Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
  5. NM_001242810.2NP_001229739.2  bromodomain testis-specific protein isoform d

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR and coding sequence compared to variant 4. The resulting isoform (d) is shorter at the N-terminus and lacks a short internal segment compared to isoform a.
    Source sequence(s)
    AC114486, AK302758, AY338951, BX648135
    Consensus CDS
    CCDS55616.1
    UniProtKB/Swiss-Prot
    Q58F21
    Related
    ENSP00000359416.2, ENST00000370389.6
    Conserved Domains (4) summary
    cd05498
    Location:199300
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:436498
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:832874
    BRD4_CDT; C-terminal domain of bromodomain protein 4
    cl02556
    Location:160
    Bromodomain; Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
  6. NM_001726.4NP_001717.3  bromodomain testis-specific protein isoform b

    See identical proteins and their annotated locations for NP_001717.3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 4. The resulting isoform (b) lacks a short internal segment compared to isoform a. Variants 1, 2, and 3 all encode the same isoform (b).
    Source sequence(s)
    AK302758, AY338951, BC047900, BX648135, DC401352
    Consensus CDS
    CCDS735.1
    UniProtKB/Swiss-Prot
    Q58F21
    Related
    ENSP00000384051.1, ENST00000402388.1
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:272373
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:509571
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:905947
    BRD4_CDT; C-terminal domain of bromodomain protein 4
  7. NM_207189.3NP_997072.2  bromodomain testis-specific protein isoform b

    See identical proteins and their annotated locations for NP_997072.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) differs in the 5' UTR and uses an alternate in-frame splice junction at the 3' end of an exon compared to variant 4. The resulting isoform (b) lacks a short internal segment compared to isoform a. Variants 1, 2, and 3 all encode the same isoform (b).
    Source sequence(s)
    AC114486, AK302758, AY338951, BC017582, BC047900, BX648135
    Consensus CDS
    CCDS735.1
    UniProtKB/Swiss-Prot
    Q58F21
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:272373
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:509571
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:905947
    BRD4_CDT; C-terminal domain of bromodomain protein 4

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    91949371..92014428
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006710853.4XP_006710916.1  bromodomain testis-specific protein isoform X1

    See identical proteins and their annotated locations for XP_006710916.1

    UniProtKB/Swiss-Prot
    Q58F21
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:272373
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:509571
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:905947
    BRD4_CDT; C-terminal domain of bromodomain protein 4
  2. XM_011542036.3XP_011540338.1  bromodomain testis-specific protein isoform X1

    See identical proteins and their annotated locations for XP_011540338.1

    UniProtKB/Swiss-Prot
    Q58F21
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:272373
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:509571
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:905947
    BRD4_CDT; C-terminal domain of bromodomain protein 4
  3. XM_006710854.4XP_006710917.1  bromodomain testis-specific protein isoform X1

    See identical proteins and their annotated locations for XP_006710917.1

    UniProtKB/Swiss-Prot
    Q58F21
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:272373
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:509571
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:905947
    BRD4_CDT; C-terminal domain of bromodomain protein 4
  4. XM_006710856.4XP_006710919.1  bromodomain testis-specific protein isoform X1

    See identical proteins and their annotated locations for XP_006710919.1

    UniProtKB/Swiss-Prot
    Q58F21
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:272373
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:509571
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:905947
    BRD4_CDT; C-terminal domain of bromodomain protein 4
  5. XM_011542033.3XP_011540335.1  bromodomain testis-specific protein isoform X1

    See identical proteins and their annotated locations for XP_011540335.1

    UniProtKB/Swiss-Prot
    Q58F21
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:272373
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:509571
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:905947
    BRD4_CDT; C-terminal domain of bromodomain protein 4
  6. XM_006710857.4XP_006710920.1  bromodomain testis-specific protein isoform X1

    See identical proteins and their annotated locations for XP_006710920.1

    UniProtKB/Swiss-Prot
    Q58F21
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:272373
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:509571
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:905947
    BRD4_CDT; C-terminal domain of bromodomain protein 4
  7. XM_011542035.3XP_011540337.1  bromodomain testis-specific protein isoform X1

    See identical proteins and their annotated locations for XP_011540337.1

    UniProtKB/Swiss-Prot
    Q58F21
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:272373
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:509571
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:905947
    BRD4_CDT; C-terminal domain of bromodomain protein 4
  8. XM_006710855.4XP_006710918.1  bromodomain testis-specific protein isoform X1

    See identical proteins and their annotated locations for XP_006710918.1

    UniProtKB/Swiss-Prot
    Q58F21
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:272373
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:509571
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:905947
    BRD4_CDT; C-terminal domain of bromodomain protein 4
  9. XM_011542032.3XP_011540334.1  bromodomain testis-specific protein isoform X1

    See identical proteins and their annotated locations for XP_011540334.1

    UniProtKB/Swiss-Prot
    Q58F21
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:272373
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:509571
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:905947
    BRD4_CDT; C-terminal domain of bromodomain protein 4
  10. XM_011542034.3XP_011540336.1  bromodomain testis-specific protein isoform X1

    See identical proteins and their annotated locations for XP_011540336.1

    UniProtKB/Swiss-Prot
    Q58F21
    Conserved Domains (4) summary
    cd05497
    Location:27133
    Bromo_Brdt_I_like; Bromodomain, Brdt_like subfamily, repeat I. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    cd05498
    Location:272373
    Bromo_Brdt_II_like; Bromodomain, Brdt_like subfamily, repeat II. Human Brdt is a testis-specific member of the BET subfamily of bromodomain proteins; the first bromodomain in Brdt has been shown to be essential for male germ cell differentiation. Bromodomains are 110 amino ...
    pfam17035
    Location:509571
    BET; Bromodomain extra-terminal - transcription regulation
    pfam17105
    Location:905947
    BRD4_CDT; C-terminal domain of bromodomain protein 4
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