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Pigm phosphatidylinositol glycan anchor biosynthesis, class M [ Mus musculus (house mouse) ]

Gene ID: 67556, updated on 30-Apr-2024

Summary

Official Symbol
Pigmprovided by MGI
Official Full Name
phosphatidylinositol glycan anchor biosynthesis, class Mprovided by MGI
Primary source
MGI:MGI:1914806
See related
Ensembl:ENSMUSG00000050229 AllianceGenome:MGI:1914806
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4933437L05Rik; C920011G20Rik
Summary
Predicted to enable mannosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be integral component of membrane. Predicted to be part of glycosylphosphatidylinositol-mannosyltransferase I complex. Is expressed in several structures, including alimentary system; aorta; genitourinary system; nervous system; and thymus. Orthologous to human PIGM (phosphatidylinositol glycan anchor biosynthesis class M). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Pigm in Genome Data Viewer
Location:
1 H3; 1 79.73 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (172204098..172211666)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (172376531..172384099)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene potassium inwardly-rectifying channel, subfamily J, member 9 Neighboring gene potassium inwardly-rectifying channel, subfamily J, member 10 Neighboring gene STARR-positive B cell enhancer ABC_E3331 Neighboring gene STARR-positive B cell enhancer ABC_E4390 Neighboring gene STARR-positive B cell enhancer mm9_chr1:174340789-174341090 Neighboring gene STARR-seq mESC enhancer starr_03060 Neighboring gene STARR-positive B cell enhancer ABC_E5854 Neighboring gene STARR-positive B cell enhancer ABC_E5855 Neighboring gene STARR-positive B cell enhancer ABC_E2020 Neighboring gene ribosomal protein SA pseudogene Neighboring gene SLAM family member 9

Genomic regions, transcripts, and products

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables alpha-1,4-mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables glycolipid mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables mannosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables mannosyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in GPI anchor biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in GPI anchor biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
part_of glycosylphosphatidylinositol-mannosyltransferase I complex IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
GPI mannosyltransferase 1
Names
GPI mannosyltransferase I
GPI-MT-I
PIG-M
phosphatidylinositol glycan, class M
phosphatidylinositol-glycan biosynthesis class M protein
NP_080510.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026234.4NP_080510.1  GPI mannosyltransferase 1

    See identical proteins and their annotated locations for NP_080510.1

    Status: VALIDATED

    Source sequence(s)
    AC074311
    Consensus CDS
    CCDS15513.1
    UniProtKB/Swiss-Prot
    Q8C2R7, Q8C917, Q99J22, Q9D315
    Related
    ENSMUSP00000052838.3, ENSMUST00000052455.4
    Conserved Domains (1) summary
    pfam05007
    Location:140408
    Mannosyl_trans; Mannosyltransferase (PIG-M)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    172204098..172211666
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)