Format

Send to:

Choose Destination

Decr1 2,4-dienoyl CoA reductase 1, mitochondrial [ Mus musculus (house mouse) ]

Gene ID: 67460, updated on 31-Jan-2019

Summary

Official Symbol
Decr1provided by MGI
Official Full Name
2,4-dienoyl CoA reductase 1, mitochondrialprovided by MGI
Primary source
MGI:MGI:1914710
See related
Ensembl:ENSMUSG00000028223
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Decr; Nadph; 1200012F07Rik
Expression
Broad expression in heart adult (RPKM 41.1), liver E18 (RPKM 22.5) and 19 other tissues See more
Orthologs

Genomic context

See Decr1 in Genome Data Viewer
Location:
4; 4 A2
Exon count:
10
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (15917240..15945507, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (15844387..15872654, complement)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene mutS homolog 6 pseudogene Neighboring gene calbindin 1 Neighboring gene microRNA 6400 Neighboring gene nibrin Neighboring gene oxidative stress induced growth inhibitor family member 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
2,4-dienoyl-CoA reductase (NADPH) activity ISO
Inferred from Sequence Orthology
more info
 
NADPH binding ISO
Inferred from Sequence Orthology
more info
 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
fatty acid beta-oxidation ISO
Inferred from Sequence Orthology
more info
 
fatty acid metabolic process IEA
Inferred from Electronic Annotation
more info
 
lipid metabolic process IEA
Inferred from Electronic Annotation
more info
 
oxidation-reduction process IEA
Inferred from Electronic Annotation
more info
 
positive regulation of cold-induced thermogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein homotetramerization ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytosol ISO
Inferred from Sequence Orthology
more info
 
mitochondrion HDA PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
2,4-dienoyl-CoA reductase, mitochondrial
NP_080448.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_026172.4NP_080448.1  2,4-dienoyl-CoA reductase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_080448.1

    Status: VALIDATED

    Source sequence(s)
    BC046972
    Consensus CDS
    CCDS17985.1
    UniProtKB/Swiss-Prot
    Q9CQ62
    UniProtKB/TrEMBL
    Q4FJK0
    Related
    ENSMUSP00000029877.8, ENSMUST00000029877.8
    Conserved Domains (2) summary
    PRK07677
    Location:59303
    PRK07677; short chain dehydrogenase; Provisional
    cd05369
    Location:57303
    TER_DECR_SDR_a; Trans-2-enoyl-CoA reductase (TER) and 2,4-dienoyl-CoA reductase (DECR), atypical (a) SDR

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

    Range
    15917240..15945507 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Support Center