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Map1lc3b microtubule-associated protein 1 light chain 3 beta [ Mus musculus (house mouse) ]

Gene ID: 67443, updated on 18-Sep-2018

Summary

Official Symbol
Map1lc3bprovided by MGI
Official Full Name
microtubule-associated protein 1 light chain 3 betaprovided by MGI
Primary source
MGI:MGI:1914693
See related
Ensembl:ENSMUSG00000031812 Vega:OTTMUSG00000043032
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Atg8; LC3b; Map1lc3; MAP1A/MAP1B; 1010001C15Rik
Expression
Ubiquitous expression in kidney adult (RPKM 80.9), adrenal adult (RPKM 77.3) and 28 other tissues See more
Orthologs

Genomic context

See Map1lc3b in Genome Data Viewer
Location:
8; 8 E1
Exon count:
4
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (121590468..121598047)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (124114368..124121947)

Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA methionine 17 (anticodon CAT) Neighboring gene 40S ribosomal protein S23-like Neighboring gene zinc finger, CCHC domain containing 14 Neighboring gene predicted gene, 46065

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC118046

Gene Ontology Provided by MGI

Function Evidence Code Pubs
microtubule binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
microtubule binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein domain specific binding ISO
Inferred from Sequence Orthology
more info
 
tubulin binding ISO
Inferred from Sequence Orthology
more info
 
ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
autophagosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
autophagosome maturation ISO
Inferred from Sequence Orthology
more info
 
autophagy IDA
Inferred from Direct Assay
more info
PubMed 
autophagy ISO
Inferred from Sequence Orthology
more info
 
autophagy of mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
autophagy of mitochondrion ISO
Inferred from Sequence Orthology
more info
 
cellular response to nitrogen starvation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cellular response to starvation ISO
Inferred from Sequence Orthology
more info
 
macroautophagy ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mucus secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of protein binding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
autolysosome IDA
Inferred from Direct Assay
more info
PubMed 
autophagosome IDA
Inferred from Direct Assay
more info
PubMed 
autophagosome ISO
Inferred from Sequence Orthology
more info
 
autophagosome membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
autophagosome membrane ISO
Inferred from Sequence Orthology
more info
 
axon ISO
Inferred from Sequence Orthology
more info
 
axoneme IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
dendrite ISO
Inferred from Sequence Orthology
more info
 
intracellular ISO
Inferred from Sequence Orthology
more info
 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
microtubule IEA
Inferred from Electronic Annotation
more info
 
microtubule associated complex ISO
Inferred from Sequence Orthology
more info
 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
microtubule-associated proteins 1A/1B light chain 3B
Names
MAP1 light chain 3-like protein 2
MAP1A/MAP1B light chain 3 B
autophagy-related protein LC3 B
autophagy-related ubiquitin-like modifier LC3 B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001364358.1NP_001351287.1  microtubule-associated proteins 1A/1B light chain 3B isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC182458
    Conserved Domains (1) summary
    cd01611
    Location:7155
    GABARAP; Ubiquitin domain of GABA-receptor-associated protein
  2. NM_026160.5NP_080436.1  microtubule-associated proteins 1A/1B light chain 3B isoform 1

    See identical proteins and their annotated locations for NP_080436.1

    Status: VALIDATED

    Source sequence(s)
    AC182458
    Consensus CDS
    CCDS22726.1
    UniProtKB/Swiss-Prot
    Q9CQV6
    Related
    ENSMUSP00000034270.9, OTTMUSP00000063259, ENSMUST00000034270.16
    Conserved Domains (1) summary
    cd01611
    Location:7120
    GABARAP; Ubiquitin domain of GABA-receptor-associated protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

    Range
    121590468..121598047
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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