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Gtf3c6 general transcription factor IIIC, polypeptide 6, alpha [ Mus musculus (house mouse) ]

Gene ID: 67371, updated on 26-Sep-2022

Summary

Official Symbol
Gtf3c6provided by MGI
Official Full Name
general transcription factor IIIC, polypeptide 6, alphaprovided by MGI
Primary source
MGI:MGI:1914621
See related
Ensembl:ENSMUSG00000019837 AllianceGenome:MGI:1914621
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2410016F19Rik
Summary
Predicted to contribute to DNA binding activity. Predicted to be involved in transcription by RNA polymerase III. Predicted to be located in nuclear body. Predicted to be part of transcription factor TFIIIC complex. Orthologous to human GTF3C6 (general transcription factor IIIC subunit 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 16.4), CNS E14 (RPKM 12.0) and 25 other tissues See more
Orthologs
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Genomic context

See Gtf3c6 in Genome Data Viewer
Location:
10; 10 B1
Exon count:
7
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (40123697..40133708, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (40247701..40257712, complement)

Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31992 Neighboring gene ribosome production factor 2 homolog Neighboring gene small nucleolar RNA, C/D box 3A Neighboring gene S-adenosylmethionine decarboxylase 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
contributes_to DNA binding ISO
Inferred from Sequence Orthology
more info
 
enables RNA polymerase III general transcription initiation factor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in transcription by RNA polymerase III IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in transcription by RNA polymerase III ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in nuclear body ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of transcription factor TFIIIC complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of transcription factor TFIIIC complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
general transcription factor 3C polypeptide 6
Names
TFIIIC 35 kDa subunit
TFIIIC35
transcription factor IIIC 35 kDa subunit
transcription factor IIIC subunit 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359491.1NP_001346420.1  general transcription factor 3C polypeptide 6 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC131684, AC164625, AI430887, AK005261, BY110346
    Consensus CDS
    CCDS87991.1
    UniProtKB/TrEMBL
    Q9DB36
    Related
    ENSMUSP00000019982.9, ENSMUST00000019982.9
    Conserved Domains (1) summary
    pfam10419
    Location:5285
    TFIIIC_sub6; TFIIIC subunit
  2. NM_001359492.1NP_001346421.1  general transcription factor 3C polypeptide 6 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC131684, AC164625, AI430887, AK007816, BU695477, BY110346
    Conserved Domains (1) summary
    pfam10419
    Location:122
    TFIIIC_sub6; TFIIIC subunit
  3. NM_001359493.1NP_001346422.1  general transcription factor 3C polypeptide 6 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC131684, AC164625, AI430887, AK007816, BY253152
    Conserved Domains (1) summary
    pfam10419
    Location:122
    TFIIIC_sub6; TFIIIC subunit
  4. NM_026113.5NP_080389.2  general transcription factor 3C polypeptide 6 isoform 2

    See identical proteins and their annotated locations for NP_080389.2

    Status: VALIDATED

    Source sequence(s)
    AC131684, AC164625, AI430887, AK007816, BY110346
    Consensus CDS
    CCDS23794.1
    UniProtKB/Swiss-Prot
    Q8R2T6, Q9D8P7
    Related
    ENSMUSP00000151091.2, ENSMUST00000217537.2
    Conserved Domains (1) summary
    pfam10419
    Location:5184
    TFIIIC_sub6; TFIIIC subunit

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000076.7 Reference GRCm39 C57BL/6J

    Range
    40123697..40133708 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)