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Sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) [ Mus musculus (house mouse) ]

Gene ID: 66945, updated on 7-Apr-2019

Summary

Official Symbol
Sdhaprovided by MGI
Official Full Name
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)provided by MGI
Primary source
MGI:MGI:1914195
See related
Ensembl:ENSMUSG00000021577
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
FP; SDH2; SDHF; C81073; 4921513A11; 1500032O14Rik; 2310034D06Rik
Expression
Ubiquitous expression in heart adult (RPKM 297.9), kidney adult (RPKM 187.0) and 28 other tissues See more
Orthologs

Genomic context

See Sdha in Genome Data Viewer
Location:
13; 13 C1
Exon count:
15
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (74322255..74350240, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (74459703..74487688, complement)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene aryl-hydrocarbon receptor repressor Neighboring gene programmed cell death 6 Neighboring gene coiled-coil domain containing 127 Neighboring gene leucine rich repeat containing 14B Neighboring gene zinc finger protein 72 Neighboring gene BCL2-like 13 (apoptosis facilitator) pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from BioSystems

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
electron transfer activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
flavin adenine dinucleotide binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
oxidoreductase activity, acting on the CH-CH group of donors IEA
Inferred from Electronic Annotation
more info
 
succinate dehydrogenase (ubiquinone) activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
succinate dehydrogenase (ubiquinone) activity ISO
Inferred from Sequence Orthology
more info
 
succinate dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
contributes_to succinate dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
electron transport chain IEA
Inferred from Electronic Annotation
more info
 
mitochondrial electron transport, succinate to ubiquinone IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nervous system development ISO
Inferred from Sequence Orthology
more info
 
oxidation-reduction process ISO
Inferred from Sequence Orthology
more info
 
respiratory electron transport chain ISO
Inferred from Sequence Orthology
more info
 
succinate metabolic process ISO
Inferred from Sequence Orthology
more info
 
tricarboxylic acid cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
membrane IEA
Inferred from Electronic Annotation
more info
 
mitochondrial inner membrane HDA PubMed 
mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
 
mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
mitochondrion HDA PubMed 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
myelin sheath HDA PubMed 
nucleolus ISO
Inferred from Sequence Orthology
more info
 
plasma membrane succinate dehydrogenase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
Names
flavoprotein subunit of complex II
NP_075770.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023281.1NP_075770.1  succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial precursor

    See identical proteins and their annotated locations for NP_075770.1

    Status: VALIDATED

    Source sequence(s)
    AK010561, AK034928
    Consensus CDS
    CCDS26643.1
    UniProtKB/Swiss-Prot
    Q8K2B3
    Related
    ENSMUSP00000022062.7, ENSMUST00000022062.7
    Conserved Domains (3) summary
    PTZ00139
    Location:35664
    PTZ00139; Succinate dehydrogenase [ubiquinone] flavoprotein subunit; Provisional
    pfam02910
    Location:513664
    Succ_DH_flav_C; Fumarate reductase flavoprotein C-term
    cl21454
    Location:85518
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

    Range
    74322255..74350240 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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