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Bzw1 basic leucine zipper and W2 domains 1 [ Mus musculus (house mouse) ]

Gene ID: 66882, updated on 26-Sep-2022

Summary

Official Symbol
Bzw1provided by MGI
Official Full Name
basic leucine zipper and W2 domains 1provided by MGI
Primary source
MGI:MGI:1914132
See related
Ensembl:ENSMUSG00000051223 AllianceGenome:MGI:1914132
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA0005; 1200015E15Rik
Summary
Predicted to be active in cytoplasm. Orthologous to human BZW1 (basic leucine zipper and W2 domains 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E11.5 (RPKM 69.8), CNS E18 (RPKM 52.7) and 24 other tissues See more
Orthologs
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Genomic context

See Bzw1 in Genome Data Viewer
Location:
1; 1 C1.3
Exon count:
12
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (58432057..58446513)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (58392898..58407354)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene aldehyde oxidase 2 Neighboring gene predicted gene 15759 Neighboring gene ribosomal protein S27 pseudogene Neighboring gene predicted gene, 53481 Neighboring gene CDC-like kinase 1 Neighboring gene peptidylprolyl isomerase (cyclophilin)-like 3 Neighboring gene Ngg1 interacting factor 3-like 1 (S. pombe)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC6434

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within regulation of translation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of translational initiation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
eIF5-mimic protein 2; basic leucine zipper and W2 domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025824.4NP_080100.1  eIF5-mimic protein 2

    See identical proteins and their annotated locations for NP_080100.1

    Status: VALIDATED

    Source sequence(s)
    AC121091, AK076560, AK161192, CJ085444
    Consensus CDS
    CCDS14971.1
    UniProtKB/Swiss-Prot
    Q3UZ94, Q9CQC6
    UniProtKB/TrEMBL
    A0A6P5PK54
    Related
    ENSMUSP00000051935.9, ENSMUST00000050552.15
    Conserved Domains (1) summary
    cd11560
    Location:217406
    W2_eIF5C_like; C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    58432057..58446513
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017322066.1XP_017177555.1  basic leucine zipper and W2 domain-containing protein 1 isoform X1

    Conserved Domains (1) summary
    cd11560
    Location:133322
    W2_eIF5C_like; C-terminal W2 domain of the eukaryotic translation initiation factor 5C and similar proteins