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Pgm2 phosphoglucomutase 2 [ Mus musculus (house mouse) ]

Gene ID: 66681, updated on 7-Feb-2023

Summary

Official Symbol
Pgm2provided by MGI
Official Full Name
phosphoglucomutase 2provided by MGI
Primary source
MGI:MGI:97564
See related
Ensembl:ENSMUSG00000029171 AllianceGenome:MGI:97564
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pgm1; Pgm-1; 3230402E02Rik
Summary
Enables phosphoglucomutase activity. Acts upstream of or within glucose metabolic process. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; liver; oocyte; respiratory system; and telencephalon. Orthologous to human PGM2 (phosphoglucomutase 2). [provided by Alliance of Genome Resources, Apr 2022]
Annotation information
Note: The name of this locus, Pgm2, was recently updated by Mouse Genomic Informatics to be consistent with mammalian orthologs identified as Pgm2. Note that this gene is frequently referred to as Pgm1 in the literature. [02 Oct 2019]
Expression
Ubiquitous expression in small intestine adult (RPKM 10.1), large intestine adult (RPKM 9.5) and 26 other tissues See more
Orthologs
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Genomic context

See Pgm2 in Genome Data Viewer
Location:
5 C3.1; 5 32.8 cM
Exon count:
15
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (64250258..64285698)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (64092919..64128355)

Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 25608 Neighboring gene RIKEN cDNA 5830416I19 gene Neighboring gene predicted gene, 22559 Neighboring gene TBC1 domain family, member 1 Neighboring gene predicted gene 15824

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables intramolecular transferase activity, phosphotransferases IEA
Inferred from Electronic Annotation
more info
 
enables isomerase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables phosphoglucomutase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables phosphoglucomutase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables phosphoglucomutase activity ISO
Inferred from Sequence Orthology
more info
 
enables phosphopentomutase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables phosphopentomutase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within glucose metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in glycogen catabolic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in organic substance metabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in purine ribonucleoside salvage IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
phosphoglucomutase-2
Names
glucose phosphomutase 2
phosphodeoxyribomutase
phosphoglucomutase 1
phosphopentomutase
NP_001343893.1
NP_079976.1
XP_006504121.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001356964.1NP_001343893.1  phosphoglucomutase-2 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AC132271
    Conserved Domains (1) summary
    PTZ00150
    Location:1558
    PTZ00150; phosphoglucomutase-2-like protein; Provisional
  2. NM_025700.3NP_079976.1  phosphoglucomutase-2 isoform 1

    See identical proteins and their annotated locations for NP_079976.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AC132271, AK014332
    Consensus CDS
    CCDS19300.1
    UniProtKB/Swiss-Prot
    Q7TSV4, Q9CRS8
    Related
    ENSMUSP00000084582.6, ENSMUST00000087324.7
    Conserved Domains (1) summary
    PTZ00150
    Location:19620
    PTZ00150; phosphoglucomutase-2-like protein; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000071.7 Reference GRCm39 C57BL/6J

    Range
    64250258..64285698
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006504058.3XP_006504121.1  phosphoglucomutase-2 isoform X1

    Conserved Domains (1) summary
    PTZ00150
    Location:1452
    PTZ00150; phosphoglucomutase-2-like protein; Provisional

RNA

  1. XR_004942550.1 RNA Sequence