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PGM2 phosphoglucomutase 2 [ Homo sapiens (human) ]

Gene ID: 55276, updated on 5-Apr-2020

Summary

Official Symbol
PGM2provided by HGNC
Official Full Name
phosphoglucomutase 2provided by HGNC
Primary source
HGNC:HGNC:8906
See related
Ensembl:ENSG00000169299 MIM:172000
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MSTP006
Expression
Ubiquitous expression in esophagus (RPKM 28.0), urinary bladder (RPKM 13.5) and 23 other tissues See more
Orthologs

Genomic context

See PGM2 in Genome Data Viewer
Location:
4p14
Exon count:
15
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (37826686..37862937)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (37828282..37864559)

Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374406 Neighboring gene ribosomal protein L21 pseudogene 45 Neighboring gene heterogeneous nuclear ribonucleoprotein R pseudogene 3 Neighboring gene TBC1 domain family member 1 Neighboring gene uncharacterized LOC105374407

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10983

Gene Ontology Provided by GOA

Function Evidence Code Pubs
magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 
phosphoglucomutase activity IEA
Inferred from Electronic Annotation
more info
 
phosphopentomutase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
deoxyribose phosphate catabolic process IEA
Inferred from Electronic Annotation
more info
 
galactose catabolic process TAS
Traceable Author Statement
more info
 
glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 
glycogen biosynthetic process TAS
Traceable Author Statement
more info
 
glycogen catabolic process TAS
Traceable Author Statement
more info
 
neutrophil degranulation TAS
Traceable Author Statement
more info
 
pentose-phosphate shunt TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytosol TAS
Traceable Author Statement
more info
 
extracellular exosome HDA PubMed 
extracellular region TAS
Traceable Author Statement
more info
 
ficolin-1-rich granule lumen TAS
Traceable Author Statement
more info
 
secretory granule lumen TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
phosphoglucomutase-2
Names
PGM 2
glucose phosphomutase 2
phosphodeoxyribomutase
NP_060760.2
XP_011512013.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018290.4NP_060760.2  phosphoglucomutase-2

    See identical proteins and their annotated locations for NP_060760.2

    Status: VALIDATED

    Source sequence(s)
    AF109360, AI955714, BC010087, BP234074
    Consensus CDS
    CCDS3443.1
    UniProtKB/Swiss-Prot
    Q96G03
    Related
    ENSP00000371393.4, ENST00000381967.9
    Conserved Domains (2) summary
    cd05799
    Location:54592
    PGM2; This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and ...
    PTZ00150
    Location:15612
    PTZ00150; phosphoglucomutase-2-like protein; Provisional

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

    Range
    37826686..37862937
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011513711.2XP_011512013.1  phosphoglucomutase-2 isoform X1

    Conserved Domains (1) summary
    cd05799
    Location:9453
    PGM2; This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and ...
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