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Slc30a7 solute carrier family 30 (zinc transporter), member 7 [ Mus musculus (house mouse) ]

Gene ID: 66500, updated on 9-May-2024

Summary

Official Symbol
Slc30a7provided by MGI
Official Full Name
solute carrier family 30 (zinc transporter), member 7provided by MGI
Primary source
MGI:MGI:1913750
See related
Ensembl:ENSMUSG00000054414 AllianceGenome:MGI:1913750
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ZnT7; ZnT-7; Zntl2; 1810059J10Rik; 2610034N15Rik; 4833428C12Rik
Summary
Predicted to enable zinc ion binding activity and zinc ion transmembrane transporter activity. Acts upstream of or within sequestering of zinc ion and zinc ion transport. Located in Golgi apparatus; cytoplasmic vesicle; and perinuclear region of cytoplasm. Is expressed in several structures, including nervous system and urinary system. Orthologous to human SLC30A7 (solute carrier family 30 member 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 7.4), limb E14.5 (RPKM 5.4) and 28 other tissues See more
Orthologs
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Genomic context

See Slc30a7 in Genome Data Viewer
Location:
3 G1; 3 50.16 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (115732622..115801079, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (115938973..116007414, complement)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A930005H10 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:115591074-115591257 Neighboring gene diphthamide biosynthesis 5 Neighboring gene predicted gene, 54180 Neighboring gene E74-like factor 1 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E4581 Neighboring gene microRNA 669n Neighboring gene STARR-positive B cell enhancer ABC_E3462 Neighboring gene exostosin-like glycosyltransferase 2 Neighboring gene predicted gene, 26344

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables monoatomic cation transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IC
Inferred by Curator
more info
PubMed 
enables zinc ion transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables zinc ion transmembrane transporter activity IDA
Inferred from Direct Assay
more info
PubMed 
enables zinc ion transmembrane transporter activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in intracellular zinc ion homeostasis IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in intracellular zinc ion homeostasis IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in monoatomic cation transport IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
involved_in zinc ion import into Golgi lumen IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in zinc ion import into Golgi lumen IDA
Inferred from Direct Assay
more info
PubMed 
involved_in zinc ion import into Golgi lumen ISO
Inferred from Sequence Orthology
more info
 
acts_upstream_of_or_within zinc ion transport IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
located_in Golgi cis cisterna membrane ISO
Inferred from Sequence Orthology
more info
 
located_in cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
is_active_in cytoplasmic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in cytoplasmic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
located_in sarcoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in sarcoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in vesicle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
zinc transporter 7
Names
solute carrier family 30 member 7
znt-like transporter 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_023214.7NP_075703.1  zinc transporter 7

    See identical proteins and their annotated locations for NP_075703.1

    Status: VALIDATED

    Source sequence(s)
    AC108909, AC131113, AK075802
    Consensus CDS
    CCDS17783.1
    UniProtKB/Swiss-Prot
    Q80Y27, Q9JKN1
    Related
    ENSMUSP00000065254.4, ENSMUST00000067485.4
    Conserved Domains (2) summary
    COG1230
    Location:31376
    CzcD; Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]
    pfam01545
    Location:48296
    Cation_efflux; Cation efflux family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    115732622..115801079 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163227.1XP_036019120.1  zinc transporter 7 isoform X1

    Conserved Domains (1) summary
    COG1230
    Location:31284
    CzcD; Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]
  2. XM_011240194.2XP_011238496.1  zinc transporter 7 isoform X2

    Conserved Domains (1) summary
    COG1230
    Location:31159
    CzcD; Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism]