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Mrpl20 mitochondrial ribosomal protein L20 [ Mus musculus (house mouse) ]

Gene ID: 66448, updated on 11-Apr-2024

Summary

Official Symbol
Mrpl20provided by MGI
Official Full Name
mitochondrial ribosomal protein L20provided by MGI
Primary source
MGI:MGI:2137221
See related
Ensembl:ENSMUSG00000029066 AllianceGenome:MGI:2137221
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610008D01Rik; 4930425I20Rik
Summary
Predicted to be a structural constituent of ribosome. Predicted to be involved in ribosomal large subunit assembly. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, including extraembryonic component; ganglia; genitourinary system; jaw; and musculoskeletal system. Orthologous to human MRPL20 (mitochondrial ribosomal protein L20). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in liver E14 (RPKM 29.5), testis adult (RPKM 27.9) and 28 other tissues See more
Orthologs
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Genomic context

See Mrpl20 in Genome Data Viewer
Location:
4 E2; 4 87.44 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (155887335..155893288)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (155802878..155808831)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene transmembrane protein 88B Neighboring gene STARR-seq mESC enhancer starr_12274 Neighboring gene ankyrin repeat domain 65 Neighboring gene STARR-positive B cell enhancer ABC_E3560 Neighboring gene cyclin L2 Neighboring gene STARR-seq mESC enhancer starr_12275 Neighboring gene STARR-positive B cell enhancer ABC_E4740 Neighboring gene aurora kinase A interacting protein 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables rRNA binding IEA
Inferred from Electronic Annotation
more info
 
enables structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
enables structural constituent of ribosome ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in mitochondrial translation NAS
Non-traceable Author Statement
more info
PubMed 
acts_upstream_of_or_within translation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in mitochondrial inner membrane NAS
Non-traceable Author Statement
more info
PubMed 
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
 
part_of mitochondrial large ribosomal subunit NAS
Non-traceable Author Statement
more info
PubMed 
is_active_in mitochondrial ribosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in mitochondrial ribosome ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
part_of ribonucleoprotein complex IEA
Inferred from Electronic Annotation
more info
 
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
large ribosomal subunit protein bL20m
Names
39S ribosomal protein L20, mitochondrial
L20mt
MRP-L20

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025570.3NP_079846.1  large ribosomal subunit protein bL20m precursor

    See identical proteins and their annotated locations for NP_079846.1

    Status: VALIDATED

    Source sequence(s)
    AK011341, AL670236, BC039985, CJ082585
    Consensus CDS
    CCDS19041.1
    UniProtKB/Swiss-Prot
    Q9CQL4, Q9D5L3
    Conserved Domains (1) summary
    pfam00453
    Location:15113
    Ribosomal_L20; Ribosomal protein L20

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    155887335..155893288
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164313.1XP_036020206.1  large ribosomal subunit protein bL20m isoform X1

    UniProtKB/Swiss-Prot
    Q9CQL4, Q9D5L3
    Related
    ENSMUSP00000030942.6, ENSMUST00000030942.13
    Conserved Domains (1) summary
    pfam00453
    Location:15113
    Ribosomal_L20; Ribosomal protein L20