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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001025444.3 → NP_001020615.1  aprataxin isoform b
See identical proteins and their annotated locations for NP_001020615.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (2) differs in the 5' UTR and the 5' coding region and intiates translation at a downstream start codon, compared to variant 1. It encodes isoform b, which has a shorter N-terminus, compared to isoform a.
- Source sequence(s)
-
AK005286, AK010516, AL833775, AL929313
- Consensus CDS
-
CCDS38712.1
- UniProtKB/TrEMBL
-
Q6IR21
- Related
- ENSMUSP00000030119.4, ENSMUST00000030119.10
- Conserved Domains (3) summary
-
- cd01278
Location:157 → 258
- aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
- pfam16278
Location:276 → 333
- zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
- pfam17913
Location:4 → 100
- FHA_2; FHA domain
-
NM_001025445.2 → NP_001020616.1  aprataxin isoform c
See identical proteins and their annotated locations for NP_001020616.1
Status: VALIDATED
- Description
- Transcript Variant: This variant (3) uses an alternate splice site in the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform c, which has a shorter N-terminus compared to isoform a.
- Source sequence(s)
-
AK010516, AL833775, AL929313
- UniProtKB/Swiss-Prot
-
Q7TQC5
- Conserved Domains (3) summary
-
- cd01278
Location:98 → 199
- aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
- pfam16278
Location:217 → 274
- zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
- pfam17913
Location:2 → 41
- FHA_2; FHA domain
-
NM_025545.4 → NP_079821.3  aprataxin isoform a
See identical proteins and their annotated locations for NP_079821.3
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
- Source sequence(s)
-
AK077351, AL929313
- Consensus CDS
-
CCDS38711.1
- UniProtKB/Swiss-Prot
- Q7TQC5, Q8BPA7, Q8C2B5, Q8K3D1, Q9CQ59
- UniProtKB/TrEMBL
-
Q6IR21
- Related
- ENSMUSP00000124264.2, ENSMUST00000068125.11
- Conserved Domains (3) summary
-
- cd00060
Location:12 → 105
- FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
- cd01278
Location:164 → 265
- aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
- pfam16278
Location:284 → 340
- zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCm39 C57BL/6J
Genomic
-
NC_000070.7Â Reference GRCm39 C57BL/6J
- Range
-
40682078..40703206 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_036164311.1 → XP_036020204.1  aprataxin isoform X3
- Conserved Domains (3) summary
-
- cd01278
Location:98 → 199
- aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
- pfam16278
Location:217 → 274
- zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
- pfam17913
Location:2 → 41
- FHA_2; FHA domain
-
XM_030253699.2 → XP_030109559.1  aprataxin isoform X3
- Conserved Domains (3) summary
-
- cd01278
Location:98 → 199
- aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
- pfam16278
Location:217 → 274
- zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
- pfam17913
Location:2 → 41
- FHA_2; FHA domain
-
XM_006538167.4 → XP_006538230.1  aprataxin isoform X2
See identical proteins and their annotated locations for XP_006538230.1
- UniProtKB/TrEMBL
-
Q6IR21
- Conserved Domains (3) summary
-
- cd01278
Location:157 → 258
- aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
- pfam16278
Location:276 → 333
- zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
- pfam17913
Location:4 → 100
- FHA_2; FHA domain
-
XM_006538169.4 → XP_006538232.1  aprataxin isoform X2
See identical proteins and their annotated locations for XP_006538232.1
- UniProtKB/TrEMBL
-
Q6IR21
- Conserved Domains (3) summary
-
- cd01278
Location:157 → 258
- aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
- pfam16278
Location:276 → 333
- zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
- pfam17913
Location:4 → 100
- FHA_2; FHA domain
-
XM_006538168.4 → XP_006538231.1  aprataxin isoform X2
See identical proteins and their annotated locations for XP_006538231.1
- UniProtKB/TrEMBL
-
Q6IR21
- Conserved Domains (3) summary
-
- cd01278
Location:157 → 258
- aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
- pfam16278
Location:276 → 333
- zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
- pfam17913
Location:4 → 100
- FHA_2; FHA domain
-
XM_006538170.5 → XP_006538233.1  aprataxin isoform X2
See identical proteins and their annotated locations for XP_006538233.1
- UniProtKB/TrEMBL
-
Q6IR21
- Conserved Domains (3) summary
-
- cd01278
Location:157 → 258
- aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
- pfam16278
Location:276 → 333
- zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
- pfam17913
Location:4 → 100
- FHA_2; FHA domain
-
XM_011250084.3 → XP_011248386.1  aprataxin isoform X1
- UniProtKB/TrEMBL
-
Q6IR21
- Conserved Domains (3) summary
-
- cd01278
Location:162 → 263
- aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
- pfam16278
Location:281 → 338
- zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
- pfam17913
Location:9 → 105
- FHA_2; FHA domain
-
XM_006538171.4 → XP_006538234.1  aprataxin isoform X3
See identical proteins and their annotated locations for XP_006538234.1
- UniProtKB/Swiss-Prot
-
Q7TQC5
- Conserved Domains (3) summary
-
- cd01278
Location:98 → 199
- aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
- pfam16278
Location:217 → 274
- zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
- pfam17913
Location:2 → 41
- FHA_2; FHA domain
-
XM_030253698.2 → XP_030109558.1  aprataxin isoform X3
- Conserved Domains (3) summary
-
- cd01278
Location:98 → 199
- aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
- pfam16278
Location:217 → 274
- zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
- pfam17913
Location:2 → 41
- FHA_2; FHA domain
-
XM_036164309.1 → XP_036020202.1  aprataxin isoform X3
- Conserved Domains (3) summary
-
- cd01278
Location:98 → 199
- aprataxin_related; aprataxin related: Aprataxin, a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome. All the members of this subgroup have the conserved HxHxHxx (where x is a hydrophobic residue) signature motif. Members of this subgroup are ...
- pfam16278
Location:217 → 274
- zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger
- pfam17913
Location:2 → 41
- FHA_2; FHA domain