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Mcts2 malignant T cell amplified sequence 2 [ Mus musculus (house mouse) ]

Gene ID: 66405, updated on 2-Nov-2024

Summary

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Official Symbol
Mcts2provided by MGI
Official Full Name
malignant T cell amplified sequence 2provided by MGI
Primary source
MGI:MGI:1913655
See related
Ensembl:ENSMUSG00000042814 AllianceGenome:MGI:1913655
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MCT-2; 2400002F11Rik
Summary
Predicted to enable RNA binding activity. Predicted to be involved in formation of translation preinitiation complex. Predicted to be located in cytoplasm. Is expressed in several structures, including alimentary system; basioccipital bone; central nervous system; future brain; and sensory organ. Orthologous to human MCTS2 (MCTS family member 2). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human all
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Genomic context

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See Mcts2 in Genome Data Viewer
Location:
2 H1; 2 75.41 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (152529091..152529871)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (152687148..152687946)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700030C14 gene Neighboring gene STARR-seq mESC enhancer starr_06065 Neighboring gene predicted gene, 31791 Neighboring gene STARR-positive B cell enhancer ABC_E2648 Neighboring gene histocompatibility 13 Neighboring gene STARR-seq mESC enhancer starr_06066 Neighboring gene STARR-seq mESC enhancer starr_06068 Neighboring gene inhibitor of DNA binding 1, HLH protein Neighboring gene high mobility group box 1-like pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Spatiotemporal expression of retrogene-host pair Mcts2/H13 in mouse embryo, and Mcts2 has no influence on H13 transcription pattern in NIH/3T3 cells. Huang Z, et al. Acta Histochem, 2014 Mar. PMID 24063864
  2. A case-by-case evolutionary analysis of four imprinted retrogenes. McCole RB, et al. Evolution, 2011 May. PMID 21166792, Free PMC Article
  3. A screen for retrotransposed imprinted genes reveals an association between X chromosome homology and maternal germ-line methylation. Wood AJ, et al. PLoS Genet, 2007 Feb 9. PMID 17291163, Free PMC Article
  4. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Federspiel JD, et al. Mol Cell Proteomics, 2019 Aug 9. PMID 31040226, Free PMC Article
  5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

See all (16) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC41042

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in formation of translation preinitiation complex IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
malignant T-cell-amplified sequence 2
Names
multiple copies T-cell malignancies 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025543.3 → NP_079819.1  malignant T-cell-amplified sequence 2

    See identical proteins and their annotated locations for NP_079819.1

    Status: VALIDATED

    Source sequence(s)
    AL845162
    Consensus CDS
    CCDS38281.1
    UniProtKB/Swiss-Prot
    Q9CQ21
    Related
    ENSMUSP00000100534.3, ENSMUST00000062148.9
    Conserved Domains (2) summary
    cd11609
    Location:4 → 80
    MCT1_N; N-terminal domain of multiple copies T cell malignancies 1 and related proteins
    cd21155
    Location:80 → 175
    PUA_MCTS-1-like; PUA RNA-binding domain of malignant T cell-amplified sequence 1 and related proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    152529091..152529871
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CQ21.1 GenPept UniProtKB/Swiss-Prot:Q9CQ21

Gene LinkOut

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