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Tpd52l2 tumor protein D52-like 2 [ Mus musculus (house mouse) ]

Gene ID: 66314, updated on 8-Jan-2023

Summary

Official Symbol
Tpd52l2provided by MGI
Official Full Name
tumor protein D52-like 2provided by MGI
Primary source
MGI:MGI:1913564
See related
Ensembl:ENSMUSG00000000827 AllianceGenome:MGI:1913564
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D54; 2810411G23Rik
Summary
Predicted to enable protein homodimerization activity. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytoplasm. Orthologous to human TPD52L2 (TPD52 like 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 19.2), bladder adult (RPKM 18.0) and 28 other tissues See more
Orthologs
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Genomic context

See Tpd52l2 in Genome Data Viewer
Location:
2; 2 H4
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (181138935..181159755)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (181497142..181517962)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 46 Neighboring gene predicted gene, 22708 Neighboring gene abhydrolase domain containing 16B Neighboring gene U1 spliceosomal RNA Neighboring gene DnaJ heat shock protein family (Hsp40) member C5 Neighboring gene uridine-cytidine kinase 1-like 1 Neighboring gene uridine-cytidine kinase 1-like 1, opposite strand

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291197.2NP_001278126.1  tumor protein D54 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform a.
    Source sequence(s)
    AL929094
    UniProtKB/Swiss-Prot
    Q9CYZ2
    UniProtKB/TrEMBL
    Q3TUJ9
    Conserved Domains (1) summary
    pfam04201
    Location:55212
    TPD52; Tumour protein D52 family
  2. NM_001291200.2NP_001278129.1  tumor protein D54 isoform c

    See identical proteins and their annotated locations for NP_001278129.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon in the 3' coding region, compared to variant 1, resulting in an isoform (c) that is shorter than isoform a.
    Source sequence(s)
    AL929094
    Consensus CDS
    CCDS71219.1
    UniProtKB/TrEMBL
    Q3TAI4, Q3TUJ9
    Related
    ENSMUSP00000000844.9, ENSMUST00000000844.15
    Conserved Domains (1) summary
    pfam04201
    Location:55197
    TPD52; Tumour protein D52 family
  3. NM_001291201.2NP_001278130.1  tumor protein D54 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (d) that is shorter than isoform a.
    Source sequence(s)
    AL929094
    UniProtKB/TrEMBL
    Q3TUJ9, Q8BKP1
    Conserved Domains (1) summary
    pfam04201
    Location:55163
    TPD52; tumor protein D52 family
  4. NM_001291202.2NP_001278131.1  tumor protein D54 isoform e

    See identical proteins and their annotated locations for NP_001278131.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks an alternate in-frame exon in the central coding region, and uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in an isoform (e) that is shorter than isoform a.
    Source sequence(s)
    AL929094
    Consensus CDS
    CCDS71220.1
    UniProtKB/TrEMBL
    Q3TUJ9, Q8BKP1
    Related
    ENSMUSP00000068888.3, ENSMUST00000069712.9
    Conserved Domains (1) summary
    pfam04201
    Location:55191
    TPD52; Tumour protein D52 family
  5. NM_001291203.2NP_001278132.1  tumor protein D54 isoform f

    See identical proteins and their annotated locations for NP_001278132.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks an alternate in-frame exon in both the central and 3' coding regions, compared to variant 1, resulting in an isoform (f) that is shorter than isoform a.
    Source sequence(s)
    AL929094
    Consensus CDS
    CCDS71221.1
    UniProtKB/TrEMBL
    Q3TUJ9, Q8BKP1
    Related
    ENSMUSP00000104428.2, ENSMUST00000108800.8
    Conserved Domains (1) summary
    pfam04201
    Location:55177
    TPD52; Tumour protein D52 family
  6. NM_001291204.2NP_001278133.1  tumor protein D54 isoform g

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) lacks three alternate exons that result in a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (g) has a distinct C-terminus and is shorter than isoform a.
    Source sequence(s)
    AL929094
    UniProtKB/TrEMBL
    Q3TAI4, Q3TUJ9
  7. NM_001373959.2NP_001360888.1  tumor protein D54 isoform h

    Status: VALIDATED

    Source sequence(s)
    AL929094
    Consensus CDS
    CCDS89610.1
    UniProtKB/TrEMBL
    A2AUD5
    Related
    ENSMUSP00000104427.4, ENSMUST00000108799.10
    Conserved Domains (1) summary
    pfam04201
    Location:55220
    TPD52; tumor protein D52 family
  8. NM_001373960.2NP_001360889.1  tumor protein D54 isoform i

    Status: VALIDATED

    Source sequence(s)
    AL929094
    Conserved Domains (1) summary
    pfam04201
    Location:55201
    TPD52; tumor protein D52 family
  9. NM_001373961.2NP_001360890.1  tumor protein D54 isoform j

    Status: VALIDATED

    Source sequence(s)
    AL929094
    Conserved Domains (1) summary
    pfam04201
    Location:55200
    TPD52; tumor protein D52 family
  10. NM_001406353.1NP_001393282.1  tumor protein D54 isoform k

    Status: VALIDATED

    Source sequence(s)
    AL929094
  11. NM_001406354.1NP_001393283.1  tumor protein D54 isoform l

    Status: VALIDATED

    Source sequence(s)
    AL929094
  12. NM_001406355.1NP_001393284.1  tumor protein D54 isoform m

    Status: VALIDATED

    Source sequence(s)
    AL929094
  13. NM_001406356.1NP_001393285.1  tumor protein D54 isoform n

    Status: VALIDATED

    Source sequence(s)
    AL929094
  14. NM_001406357.1NP_001393286.1  tumor protein D54 isoform o

    Status: VALIDATED

    Source sequence(s)
    AL929094
  15. NM_001406358.1NP_001393287.1  tumor protein D54 isoform p

    Status: VALIDATED

    Source sequence(s)
    AL929094
  16. NM_001406359.1NP_001393288.1  tumor protein D54 isoform q

    Status: VALIDATED

    Source sequence(s)
    AL929094
  17. NM_001406360.1NP_001393289.1  tumor protein D54 isoform r

    Status: VALIDATED

    Source sequence(s)
    AL929094
  18. NM_001406361.1NP_001393290.1  tumor protein D54 isoform s

    Status: VALIDATED

    Source sequence(s)
    AL929094
  19. NM_001406362.1NP_001393291.1  tumor protein D54 isoform t

    Status: VALIDATED

    Source sequence(s)
    AL929094
  20. NM_001406363.1NP_001393292.1  tumor protein D54 isoform u

    Status: VALIDATED

    Source sequence(s)
    AL929094
  21. NM_025482.4NP_079758.2  tumor protein D54 isoform b

    See identical proteins and their annotated locations for NP_079758.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a.
    Source sequence(s)
    AL929094
    Consensus CDS
    CCDS17214.1
    UniProtKB/Swiss-Prot
    Q3TVY1, Q9CYZ2
    UniProtKB/TrEMBL
    Q3TUJ9
    Related
    ENSMUSP00000117690.2, ENSMUST00000149163.8
    Conserved Domains (1) summary
    pfam04201
    Location:55211
    TPD52; Tumour protein D52 family

RNA

  1. NR_111899.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) lacks an alternate exon in both the 5' and 3' regions, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AL929094
  2. NR_176048.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL929094
  3. NR_176049.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL929094
  4. NR_176050.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL929094

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    181138935..181159755
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500701.2XP_006500764.1  tumor protein D54 isoform X4

    Related
    ENSMUST00000183956.8
    Conserved Domains (1) summary
    pfam04201
    Location:55139
    TPD52; tumor protein D52 family
  2. XM_036162449.1XP_036018342.1  tumor protein D54 isoform X3

    Conserved Domains (1) summary
    pfam04201
    Location:55138
    TPD52; tumor protein D52 family
  3. XM_006500693.4XP_006500756.1  tumor protein D54 isoform X1

    Conserved Domains (1) summary
    pfam04201
    Location:55221
    TPD52; tumor protein D52 family
  4. XM_036162448.1XP_036018341.1  tumor protein D54 isoform X2

    Conserved Domains (1) summary
    pfam04201
    Location:55158
    TPD52; tumor protein D52 family