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Isoc1 isochorismatase domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 66307, updated on 27-Feb-2024

Summary

Official Symbol
Isoc1provided by MGI
Official Full Name
isochorismatase domain containing 1provided by MGI
Primary source
MGI:MGI:1913557
See related
Ensembl:ENSMUSG00000024601 AllianceGenome:MGI:1913557
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610034N03Rik
Summary
Predicted to be located in peroxisome. Predicted to be active in cytoplasm. Is expressed in brain. Orthologous to human ISOC1 (isochorismatase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in subcutaneous fat pad adult (RPKM 28.1), genital fat pad adult (RPKM 26.3) and 28 other tissues See more
Orthologs
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Genomic context

See Isoc1 in Genome Data Viewer
Location:
18 D3; 18 33.71 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (58792554..58812642)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (58659482..58679570)

Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_44701 Neighboring gene solute carrier family 27 (fatty acid transporter), member 6 Neighboring gene predicted gene, 23270 Neighboring gene STARR-seq mESC enhancer starr_44702 Neighboring gene STARR-seq mESC enhancer starr_44704 Neighboring gene predicted gene, 57652 Neighboring gene ADAM metallopeptidase with thrombospondin type 1 motif 19 Neighboring gene STARR-seq mESC enhancer starr_44705 Neighboring gene ribosomal protein S2 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in peroxisome ISO
Inferred from Sequence Orthology
more info
 
located_in peroxisome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 

General protein information

Preferred Names
isochorismatase domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025478.3NP_079754.2  isochorismatase domain-containing protein 1

    See identical proteins and their annotated locations for NP_079754.2

    Status: PROVISIONAL

    Source sequence(s)
    AC158924
    Consensus CDS
    CCDS29265.1
    UniProtKB/Swiss-Prot
    Q3U677, Q91V64
    UniProtKB/TrEMBL
    A0A494B952
    Related
    ENSMUSP00000025503.9, ENSMUST00000025503.10
    Conserved Domains (1) summary
    cd01012
    Location:115269
    YcaC_related; YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000084.7 Reference GRCm39 C57BL/6J

    Range
    58792554..58812642
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)