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ISOC1 isochorismatase domain containing 1 [ Homo sapiens (human) ]

Gene ID: 51015, updated on 1-Jun-2020

Summary

Official Symbol
ISOC1provided by HGNC
Official Full Name
isochorismatase domain containing 1provided by HGNC
Primary source
HGNC:HGNC:24254
See related
Ensembl:ENSG00000066583
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CGI-111
Expression
Ubiquitous expression in endometrium (RPKM 57.7), liver (RPKM 27.5) and 24 other tissues See more
Orthologs

Genomic context

See ISOC1 in Genome Data Viewer
Location:
5q23.3
Exon count:
5
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (129094749..129114028)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (128430442..128449721)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene solute carrier family 27 member 6 Neighboring gene uncharacterized LOC102723638 Neighboring gene uncharacterized LOC102723654 Neighboring gene microRNA 4633 Neighboring gene uncharacterized LOC107986367 Neighboring gene uncharacterized LOC105379169

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
molecular_function ND
No biological Data available
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peroxisome ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 

General protein information

Preferred Names
isochorismatase domain-containing protein 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_016048.2NP_057132.2  isochorismatase domain-containing protein 1

    See identical proteins and their annotated locations for NP_057132.2

    Status: VALIDATED

    Source sequence(s)
    BC014105, BG715081
    Consensus CDS
    CCDS43357.1
    UniProtKB/Swiss-Prot
    Q96CN7
    Related
    ENSP00000173527.5, ENST00000173527.6
    Conserved Domains (1) summary
    cd01012
    Location:116270
    YcaC_related; YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them. ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    129094749..129114028
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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