Tma16 translation machinery associated 16 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tma16provided by MGI
Official Full Name: translation machinery associated 16provided by MGI
Primary source: MGI:MGI:1913532
See related: Ensembl:ENSMUSG00000025591 AllianceGenome:MGI:1913532
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1810029B16Rik
Summary: Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in nucleus. Is expressed in liver lobe and urethra. Orthologous to human TMA16 (translation machinery associated 16 homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E11.5 (RPKM 3.1), CNS E14 (RPKM 2.3) and 24 other tissues See more
Orthologs: human all
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Genomic context

Location:: 8; 8 B3.1

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (66928995..66939182, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (66476343..66486530, complement)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

UniSTS:495977 (e-PCR)
- UniSTS:495977

Avpr1b (e-PCR), detects polymorphism
- UniSTS:495977

px-38e3 (e-PCR)
- UniSTS:257695

Homology

Homologs of the Tma16 gene: The Tma16 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, and frog.
Orthologs from Annotation Pipeline: 499 organisms have orthologs with human gene Tma16
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables preribosome binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info
involved_in ribosomal large subunit biogenesis	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within ribosome biogenesis	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info	PubMed

General protein information

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Preferred Names: translation machinery-associated protein 16

Names: UPF0534 protein C4orf43 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001357208.1 → NP_001344137.1 translation machinery-associated protein 16 isoform 2

Status: VALIDATED

Source sequence(s)

AC122800, AK031875, BC016246

Conserved Domains (1) summary

pfam11176
Location:3 → 99

Tma16; Translation machinery-associated protein 16
NM_025465.3 → NP_079741.1 translation machinery-associated protein 16 isoform 1

See identical proteins and their annotated locations for NP_079741.1

Status: VALIDATED

Source sequence(s)

AC122800, AK031875, BC034844, BF020125

Consensus CDS

CCDS40353.1

UniProtKB/Swiss-Prot

Q05DD8, Q9CR02

UniProtKB/TrEMBL

A0A8C6IIB1

Related

ENSMUSP00000026681.6, ENSMUST00000026681.7

Conserved Domains (1) summary

pfam11176
Location:13 → 161

DUF2962; Protein of unknown function (DUF2962)