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Pno1 partner of NOB1 homolog [ Mus musculus (house mouse) ]

Gene ID: 66249, updated on 5-Mar-2024

Summary

Official Symbol
Pno1provided by MGI
Official Full Name
partner of NOB1 homologprovided by MGI
Primary source
MGI:MGI:1913499
See related
Ensembl:ENSMUSG00000020116 AllianceGenome:MGI:1913499
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Emi3; Imi3; 1810003N24Rik
Summary
Predicted to enable RNA binding activity. Predicted to be located in nucleoplasm. Predicted to be active in nucleolus. Is expressed in several structures, including adrenal gland; alimentary system; central nervous system; heart; and immune system. Orthologous to human PNO1 (partner of NOB1 homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in placenta adult (RPKM 11.8), CNS E11.5 (RPKM 8.6) and 27 other tissues See more
Orthologs
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Genomic context

Location:
11 A2; 11 9.79 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (17153198..17161589, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (17203198..17211589, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_28703 Neighboring gene 60S ribosomal protein L39 pseudogene Neighboring gene protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) Neighboring gene STARR-seq mESC enhancer starr_28704 Neighboring gene STARR-positive B cell enhancer ABC_E3933 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:17111656-17111843 Neighboring gene dynein axonemal assembly factor 10 Neighboring gene STARR-seq mESC enhancer starr_28705 Neighboring gene C1D nuclear receptor co-repressor

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in ribosomal small subunit biogenesis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of small-subunit processome ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
RNA-binding protein PNO1
Names
expressed during mesenchymal induction 3
induced during mesenchymal induction 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025443.2NP_079719.1  RNA-binding protein PNO1

    See identical proteins and their annotated locations for NP_079719.1

    Status: VALIDATED

    Source sequence(s)
    AI837771, AK007324, BY034432
    Consensus CDS
    CCDS24449.1
    UniProtKB/Swiss-Prot
    Q9CPS7
    Related
    ENSMUSP00000020317.8, ENSMUST00000020317.8
    Conserved Domains (2) summary
    smart00322
    Location:173225
    KH; K homology RNA-binding domain
    COG1094
    Location:68243
    Krr1; rRNA processing protein Krr1/Pno1, contains KH domain [Translation, ribosomal structure and biogenesis]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    17153198..17161589 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)