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Cox7b cytochrome c oxidase subunit 7B [ Mus musculus (house mouse) ]

Gene ID: 66142, updated on 13-Oct-2022

Summary

Official Symbol
Cox7bprovided by MGI
Official Full Name
cytochrome c oxidase subunit 7Bprovided by MGI
Primary source
MGI:MGI:1913392
See related
Ensembl:ENSMUSG00000031231 AllianceGenome:MGI:1913392
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1110004F07Rik
Summary
Predicted to enable cytochrome-c oxidase activity. Predicted to be involved in central nervous system development. Located in mitochondrion. Is expressed in several structures, including alimentary system; heart; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in linear skin defects with multiple congenital anomalies 2. Orthologous to human COX7B (cytochrome c oxidase subunit 7B). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in heart adult (RPKM 288.1), liver E18 (RPKM 161.7) and 25 other tissues See more
Orthologs
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Genomic context

See Cox7b in Genome Data Viewer
Location:
X; X D
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (105059306..105066056)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (106015700..106022450)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene ATRX, chromatin remodeler Neighboring gene predicted gene, 23656 Neighboring gene magnesium transporter 1 Neighboring gene ATPase, Cu++ transporting, alpha polypeptide Neighboring gene toll-like receptor 13

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC107263

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables cytochrome-c oxidase activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in central nervous system development ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial respirasome IEA
Inferred from Electronic Annotation
more info
 
part_of mitochondrial respiratory chain complex IV ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of respiratory chain complex IV IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
cytochrome c oxidase subunit 7B, mitochondrial
Names
cytochrome c oxidase polypeptide VIIb
cytochrome c oxidase subunit VIIb
NP_079655.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025379.2NP_079655.1  cytochrome c oxidase subunit 7B, mitochondrial precursor

    See identical proteins and their annotated locations for NP_079655.1

    Status: VALIDATED

    Source sequence(s)
    BC089538
    Consensus CDS
    CCDS41096.1
    UniProtKB/Swiss-Prot
    P56393
    UniProtKB/TrEMBL
    Q5FW98
    Related
    ENSMUSP00000033582.5, ENSMUST00000033582.5
    Conserved Domains (1) summary
    pfam05392
    Location:179
    COX7B; Cytochrome C oxidase chain VIIB

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    105059306..105066056
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)