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TMEM236 transmembrane protein 236 [ Homo sapiens (human) ]

Gene ID: 653567, updated on 5-Jan-2022


Official Symbol
TMEM236provided by HGNC
Official Full Name
transmembrane protein 236provided by HGNC
Primary source
See related
Gene type
protein coding
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM23A; FAM23B; bA16O1.2; bA162I21.2
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Nov 2021]
Annotation information
Note: In the NCBI Build 37.2 reference assembly, TMEM236 (FAM23A) and FAM23B are duplicate genes in close proximity to each other on chromosome 10. In July 2010, the Genome Reference Consortium determined that the region contains a duplication error. The clone on which FAM23B was based (AL928729) will be removed from the reference assembly and only TMEM236 will be present in the assembly. [13 Feb 2013]
Biased expression in small intestine (RPKM 7.1), duodenum (RPKM 4.6) and 2 other tissues See more
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Genomic context

See TMEM236 in Genome Data Viewer
Exon count:
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (17752110..17800916)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (17794200..17842867)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene STAM divergent transcript Neighboring gene signal transducing adaptor molecule Neighboring gene uncharacterized LOC107984212 Neighboring gene mannose receptor C-type 1 Neighboring gene microRNA 511 Neighboring gene solute carrier family 39 member 12 Neighboring gene SLC39A12 antisense RNA 1

Genomic regions, transcripts, and products


  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018


Products Interactant Other Gene Complex Source Pubs Description

General gene information



Clone Names

  • FLJ59050

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info

General protein information

Preferred Names
transmembrane protein 236
family with sequence similarity 23, member A
family with sequence similarity 23, member B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001098844.3NP_001092314.1  transmembrane protein 236

    See identical proteins and their annotated locations for NP_001092314.1

    Status: VALIDATED

    Source sequence(s)
    AL139238, BC157856, BX097915
    Consensus CDS
    ENSP00000366715.1, ENST00000377495.2

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly


  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011519626.2XP_011517928.1  transmembrane protein 236 isoform X2

  2. XM_011519628.1XP_011517930.1  transmembrane protein 236 isoform X4

  3. XM_011519627.2XP_011517929.1  transmembrane protein 236 isoform X3

    See identical proteins and their annotated locations for XP_011517929.1

  4. XM_017016574.1XP_016872063.1  transmembrane protein 236 isoform X1

  5. XM_011519629.1XP_011517931.1  transmembrane protein 236 isoform X5

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001013629.1: Suppressed sequence

    NM_001013629.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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