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RUSF1 RUS family member 1 [ Homo sapiens (human) ]

Gene ID: 64755, updated on 20-Jun-2020

Summary

Official Symbol
RUSF1provided by HGNC
Official Full Name
RUS family member 1provided by HGNC
Primary source
HGNC:HGNC:25848
See related
Ensembl:ENSG00000140688
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RUS; C16orf58
Summary
This gene encodes a putative transmembrane protein containing a conserved DUF647 domain that may be involved in protein-protein interaction. The encoded protein is related to a plant protein that participates in ultraviolet B light-sensing during root morphogenesis. [provided by RefSeq, Feb 2013]
Expression
Ubiquitous expression in ovary (RPKM 35.8), thyroid (RPKM 32.9) and 25 other tissues See more
Orthologs

Genomic context

See RUSF1 in Genome Data Viewer
Location:
16p11.2
Exon count:
13
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (31489475..31508391, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (31500796..31519740, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene armadillo repeat containing 5 Neighboring gene transforming growth factor beta 1 induced transcript 1 Neighboring gene solute carrier family 5 member 2 Neighboring gene alpha hemoglobin stabilizing protein Neighboring gene long intergenic non-protein coding RNA 2190 Neighboring gene vomeronasal 1 receptor 64 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13868

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane HDA PubMed 

General protein information

Preferred Names
RUS family member 1; RUS1 family protein C16orf58
Names
RUS1 homolog
UPF0420 protein C16orf58
root UVB sensitivity

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_033149.1 RefSeqGene

    Range
    5029..23945
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_022744.4NP_073581.2  RUS family member 1

    See identical proteins and their annotated locations for NP_073581.2

    Status: VALIDATED

    Source sequence(s)
    AC026471, AK023930, BC000822, DA742232
    Consensus CDS
    CCDS10715.1
    UniProtKB/Swiss-Prot
    Q96GQ5
    UniProtKB/TrEMBL
    A0A024QZE6
    Related
    ENSP00000317579.2, ENST00000327237.7
    Conserved Domains (1) summary
    pfam04884
    Location:67303
    DUF647; Vitamin B6 photo-protection and homoeostasis

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    31489475..31508391 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017023570.1XP_016879059.1  RUS1 family protein C16orf58 isoform X1

RNA

  1. XR_950831.3 RNA Sequence

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