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TMEM191C transmembrane protein 191C [ Homo sapiens (human) ]

Gene ID: 645426, updated on 26-Oct-2022

Summary

Official Symbol
TMEM191Cprovided by HGNC
Official Full Name
transmembrane protein 191Cprovided by HGNC
Primary source
HGNC:HGNC:33601
See related
Ensembl:ENSG00000206140 AllianceGenome:HGNC:33601
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis (RPKM 17.3), spleen (RPKM 1.4) and 2 other tissues See more
Orthologs
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Genomic context

See TMEM191C in Genome Data Viewer
Location:
22q11.21
Exon count:
10
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (21467387..21469935)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (21878432..21880964, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (21821676..21824224)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA U13 Neighboring gene HIC ZBTB transcriptional repressor 2 Neighboring gene phosphatidylinositol 4-kinase alpha pseudogene 2 Neighboring gene small nucleolar RNA U13

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • FLJ36990, AC023490.1

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein 191C
Names
KB-1323B2.6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001207052.2NP_001193981.2  transmembrane protein 191C isoform 2

    Status: VALIDATED

    Source sequence(s)
    AP000557
    Consensus CDS
    CCDS82695.2
    Related
    ENSP00000489706.2, ENST00000621561.5
    Conserved Domains (1) summary
    pfam15194
    Location:196300
    TMEM191C; TMEM191C family
  2. NM_001388354.1NP_001375283.1  transmembrane protein 191C isoform 1

    Status: VALIDATED

    Source sequence(s)
    AP000557
    Consensus CDS
    CCDS93125.1
    UniProtKB/TrEMBL
    A0A1B0GW53
    Related
    ENSP00000490781.2, ENST00000536718.3
    Conserved Domains (2) summary
    TIGR02168
    Location:1222
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam15194
    Location:182302
    TMEM191C; TMEM191C family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    21467387..21469935
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    21878432..21880964 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)