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TMEM267 transmembrane protein 267 [ Homo sapiens (human) ]

Gene ID: 64417, updated on 10-Oct-2024

Summary

Official Symbol
TMEM267provided by HGNC
Official Full Name
transmembrane protein 267provided by HGNC
Primary source
HGNC:HGNC:26139
See related
Ensembl:ENSG00000151881 AllianceGenome:HGNC:26139
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C5orf28
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in thyroid (RPKM 13.3), prostate (RPKM 2.9) and 24 other tissues See more
Orthologs
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Genomic context

See TMEM267 in Genome Data Viewer
Location:
5p12
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (43444252..43484387, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (43697085..43737220, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (43444354..43484489, complement)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene 60S acidic ribosomal protein P1-like Neighboring gene C-C motif chemokine ligand 28 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22538 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15993 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 15994 Neighboring gene Sharpr-MPRA regulatory region 10963 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr5:43483998-43484841 Neighboring gene C5orf34 antisense RNA 1 Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_85282 Neighboring gene chromosome 5 open reading frame 34 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene 19 Neighboring gene uncharacterized LOC124900190 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22540

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ21657, MGC90226, MGC149524

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
transmembrane protein 267
Names
transmembrane protein C5orf28

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001377394.1NP_001364323.1  transmembrane protein 267

    Status: VALIDATED

    Source sequence(s)
    AC025457
    Consensus CDS
    CCDS3945.1
    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
    UniProtKB/TrEMBL
    D6RAV6
    Related
    ENSP00000422881.1, ENST00000512085.5
  2. NM_001377395.1NP_001364324.1  transmembrane protein 267

    Status: VALIDATED

    Source sequence(s)
    AC025457
    Consensus CDS
    CCDS3945.1
    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
    UniProtKB/TrEMBL
    D6RAV6
  3. NM_001377396.1NP_001364325.1  transmembrane protein 267

    Status: VALIDATED

    Source sequence(s)
    AC025457
    Consensus CDS
    CCDS3945.1
    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
    UniProtKB/TrEMBL
    D6RAV6
  4. NM_001377397.1NP_001364326.1  transmembrane protein 267

    Status: VALIDATED

    Source sequence(s)
    AC025457
    Consensus CDS
    CCDS3945.1
    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
    UniProtKB/TrEMBL
    D6RAV6
  5. NM_001377398.1NP_001364327.1  transmembrane protein 267

    Status: VALIDATED

    Source sequence(s)
    AC025457
    Consensus CDS
    CCDS3945.1
    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
    UniProtKB/TrEMBL
    D6RAV6
  6. NM_001377399.1NP_001364328.1  transmembrane protein 267

    Status: VALIDATED

    Source sequence(s)
    AC025457
    Consensus CDS
    CCDS3945.1
    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
    UniProtKB/TrEMBL
    D6RAV6
  7. NM_001377400.1NP_001364329.1  transmembrane protein 267

    Status: VALIDATED

    Source sequence(s)
    AC025457
    Consensus CDS
    CCDS3945.1
    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
    UniProtKB/TrEMBL
    D6RAV6
  8. NM_001377401.1NP_001364330.1  transmembrane protein 267

    Status: VALIDATED

    Source sequence(s)
    AC025457
    Consensus CDS
    CCDS3945.1
    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
    UniProtKB/TrEMBL
    D6RAV6
    Related
    ENSP00000424720.1, ENST00000506860.1
  9. NM_001377402.1NP_001364331.1  transmembrane protein 267

    Status: VALIDATED

    Source sequence(s)
    AC025457
    Consensus CDS
    CCDS3945.1
    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
    UniProtKB/TrEMBL
    D6RAV6
  10. NM_001377403.1NP_001364332.1  transmembrane protein 267

    Status: VALIDATED

    Source sequence(s)
    AC025457
    Consensus CDS
    CCDS3945.1
    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
    UniProtKB/TrEMBL
    D6RAV6
    Related
    ENSP00000426067.1, ENST00000500337.6
  11. NM_022483.5NP_071928.2  transmembrane protein 267

    See identical proteins and their annotated locations for NP_071928.2

    Status: VALIDATED

    Source sequence(s)
    AC025457, DA028175, DA035926
    Consensus CDS
    CCDS3945.1
    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
    UniProtKB/TrEMBL
    D6RAV6
    Related
    ENSP00000380270.3, ENST00000397080.8

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    43444252..43484387 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047417517.1XP_047273473.1  transmembrane protein 267 isoform X1

    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
  2. XM_011514075.4XP_011512377.1  transmembrane protein 267 isoform X1

    See identical proteins and their annotated locations for XP_011512377.1

    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
    UniProtKB/TrEMBL
    D6RAV6
  3. XM_047417516.1XP_047273472.1  transmembrane protein 267 isoform X1

    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    43697085..43737220 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054353126.1XP_054209101.1  transmembrane protein 267 isoform X1

    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
  2. XM_054353125.1XP_054209100.1  transmembrane protein 267 isoform X1

    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2
  3. XM_054353124.1XP_054209099.1  transmembrane protein 267 isoform X1

    UniProtKB/Swiss-Prot
    B2RDA6, Q0VDI3, Q9H6Z2