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FAM25A family with sequence similarity 25 member A [ Homo sapiens (human) ]

Gene ID: 643161, updated on 10-Oct-2023

Summary

Official Symbol
FAM25Aprovided by HGNC
Official Full Name
family with sequence similarity 25 member Aprovided by HGNC
Primary source
HGNC:HGNC:23436
See related
Ensembl:ENSG00000188100 AllianceGenome:HGNC:23436
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
bA96C23.5
Expression
Biased expression in esophagus (RPKM 44.0) and skin (RPKM 23.0) See more
Orthologs
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Genomic context

See FAM25A in Genome Data Viewer
Location:
10q23.2
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (87020294..87024730)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (87903926..87908365)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (88780051..88784487)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:88730527-88731726 Neighboring gene uncharacterized LOC124902474 Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 11 Neighboring gene BMS1 pseudogene 3 Neighboring gene MPRA-validated peak1043 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3702 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:88779570-88780070 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:88780071-88780571 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:88784270-88785122 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:88785123-88785973 Neighboring gene RNA, U6 small nuclear 529, pseudogene Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3703 Neighboring gene glutamate dehydrogenase 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3704 Neighboring gene NANOG hESC enhancer GRCh37_chr10:88852612-88853149 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2576 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2577 Neighboring gene shieldin complex subunit 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
protein FAM25A
Names
Protein FAM25C
Protein FAM25G
protein FAM25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001146157.3NP_001139629.1  protein FAM25A

    See identical proteins and their annotated locations for NP_001139629.1

    Status: VALIDATED

    Source sequence(s)
    AL136982
    Consensus CDS
    CCDS44451.1
    UniProtKB/Swiss-Prot
    B2RV02, B3EWG3, B3EWG5, B3EWG6, Q5VTM1
    UniProtKB/TrEMBL
    B7ZW47
    Related
    ENSP00000342790.4, ENST00000343959.5
    Conserved Domains (1) summary
    pfam15825
    Location:2488
    FAM25; FAM25 family

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    87020294..87024730
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    87903926..87908365
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)