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AGAP11 ArfGAP with GTPase domain, ankyrin repeat and PH domain 11 [ Homo sapiens (human) ]

Gene ID: 119385, updated on 5-Mar-2024

Summary

Official Symbol
AGAP11provided by HGNC
Official Full Name
ArfGAP with GTPase domain, ankyrin repeat and PH domain 11provided by HGNC
Primary source
HGNC:HGNC:29421
See related
Ensembl:ENSG00000271880 AllianceGenome:HGNC:29421
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable GTPase activator activity and metal ion binding activity. Predicted to be involved in regulation of catalytic activity. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in fat (RPKM 52.1), prostate (RPKM 22.0) and 20 other tissues See more
Orthologs
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Genomic context

See AGAP11 in Genome Data Viewer
Location:
10q23.2
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (86970336..87010226)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (87854045..87893860)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (88730093..88769983)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene bone morphogenetic protein receptor type 1A Neighboring gene RNA, U1 small nuclear 19, pseudogene Neighboring gene Sharpr-MPRA regulatory region 4131 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3698 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:88700126-88700626 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:88704401-88704974 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:88713843-88714442 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:88715044-88715643 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:88718646-88719245 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr10:88720446-88721046 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:88721647-88722246 Neighboring gene multimerin 2 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3700 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3699 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:88726172-88726925 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:88726926-88727678 Neighboring gene Sharpr-MPRA regulatory region 6517 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr10:88730527-88731726 Neighboring gene uncharacterized LOC124902474 Neighboring gene ADIRF antisense RNA 1 Neighboring gene synuclein gamma Neighboring gene adipogenesis regulatory factor Neighboring gene MPRA-validated peak1043 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 3702 Neighboring gene BMS1 pseudogene 3 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:88779570-88780070 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr10:88780071-88780571 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:88784270-88785122 Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr10:88785123-88785973 Neighboring gene family with sequence similarity 25 member A Neighboring gene RNA, U6 small nuclear 529, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • ankyrin repeat and GTPase domain Arf GTPase activating protein 11
  • arf-GAP with GTPase, ANK repeat and PH domain-containing protein 11

Clone Names

  • KIAA1975

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in activation of GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_171046.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL136982
    Related
    ENST00000433214.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    86970336..87010226
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    87854045..87893860
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_133447.3: Suppressed sequence

    Description
    NM_133447.3: This RefSeq was removed because it is now thought that this gene does not encode a protein.