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UBTFL1 upstream binding transcription factor like 1 [ Homo sapiens (human) ]

Gene ID: 642623, updated on 5-Jan-2022

Summary

Official Symbol
UBTFL1provided by HGNC
Official Full Name
upstream binding transcription factor like 1provided by HGNC
Primary source
HGNC:HGNC:14533
See related
Ensembl:ENSG00000255009 MIM:613696
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HMGPI; C11orf27
Summary
UBTFL1 is a preimplantation-specific gene and is involved in early development, implantation, and embryonic stem (ES) cell derivation (summary by Yamada et al., 2010 [PubMed 19915186]).[supplied by OMIM, Jan 2011]
Orthologs
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Genomic context

See UBTFL1 in Genome Data Viewer
Location:
11q14.3
Exon count:
1
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (90085950..90087131)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (89819118..89820299)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 49C Neighboring gene ankyrin repeat domain 33B pseudogene Neighboring gene tripartite motif containing 64E, pseudogene Neighboring gene N-acetylated alpha-linked acidic dipeptidase 2 Neighboring gene cysteine and histidine rich domain containing 1

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in blastocyst growth IEA
Inferred from Electronic Annotation
more info
 
involved_in embryo implantation IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
upstream-binding factor 1-like protein 1
Names
putative upstream-binding factor 1-like protein 1
upstream binding transcription factor, RNA polymerase I-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001143975.1NP_001137447.1  upstream-binding factor 1-like protein 1

    See identical proteins and their annotated locations for NP_001137447.1

    Status: VALIDATED

    Source sequence(s)
    AP000827
    Consensus CDS
    CCDS44704.1
    UniProtKB/Swiss-Prot
    P0CB47
    Related
    ENSP00000485108.1, ENST00000530464.2
    Conserved Domains (1) summary
    cd01390
    Location:100165
    HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    90085950..90087131
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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