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IQANK1 IQ motif and ankyrin repeat containing 1 [ Homo sapiens (human) ]

Gene ID: 642574, updated on 26-Oct-2022

Summary

Official Symbol
IQANK1provided by HGNC
Official Full Name
IQ motif and ankyrin repeat containing 1provided by HGNC
Primary source
HGNC:HGNC:49576
See related
Ensembl:ENSG00000203499 MIM:618942; AllianceGenome:HGNC:49576
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FAM83HAS1; FAM83H-AS1; onco-lncRNA-3
Summary
Predicted to be involved in regulation of barbed-end actin filament capping. Predicted to be active in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See IQANK1 in Genome Data Viewer
Location:
8q24.3
Exon count:
16
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (143734139..143790645)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (144890576..144947138)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (144816309..144872815)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 4007 Neighboring gene family with sequence similarity 83 member H Neighboring gene microRNA 4664 Neighboring gene SREBF pathway regulator in golgi 1 pseudogene Neighboring gene scribble planar cell polarity protein Neighboring gene microRNA 937 Neighboring gene poly(U) binding splicing factor 60 Neighboring gene uncharacterized LOC107986985

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Clone Names

  • FLJ33892, FLJ42085, FLJ43864

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in regulation of barbed-end actin filament capping IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
IQ motif and ankyrin repeat domain-containing protein 1
Names
FAM83H antisense RNA 1 (head to head)
IQ motif and ankyrin repeat domain-containing protein LOC642574
putative IQ motif and ankyrin repeat domain-containing protein LOC642574

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001381874.1NP_001368803.1  IQ motif and ankyrin repeat domain-containing protein 1 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC105219
    Consensus CDS
    CCDS94353.1
    UniProtKB/Swiss-Prot
    A0A1B0GTG1
    Related
    ENSP00000489685.1, ENST00000527139.7
    Conserved Domains (3) summary
    PTZ00322
    Location:196265
    PTZ00322; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase; Provisional
    sd00045
    Location:191222
    ANK; ANK repeat [structural motif]
    pfam12781
    Location:430536
    AAA_9; ATP-binding dynein motor region D5
  2. NM_001381875.1NP_001368804.1  IQ motif and ankyrin repeat domain-containing protein 1 isoform 2

    Status: REVIEWED

    Source sequence(s)
    AC105219
    Consensus CDS
    CCDS94352.1
    UniProtKB/TrEMBL
    A0A1B0GUK7
    Related
    ENSP00000490151.1, ENST00000533004.5

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    143734139..143790645
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047422100.1XP_047278056.1  IQ motif and ankyrin repeat domain-containing protein 1 isoform X2

  2. XM_047422102.1XP_047278058.1  IQ motif and ankyrin repeat domain-containing protein 1 isoform X4

  3. XM_047422099.1XP_047278055.1  IQ motif and ankyrin repeat domain-containing protein 1 isoform X1

  4. XM_047422101.1XP_047278057.1  IQ motif and ankyrin repeat domain-containing protein 1 isoform X3

  5. XM_017014127.2XP_016869616.1  IQ motif and ankyrin repeat domain-containing protein 1 isoform X5

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NT_187571.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    211186..267692
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    144890576..144947138
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)