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Iqank1 IQ motif and ankyrin repeat containing 1 [ Mus musculus (house mouse) ]

Gene ID: 432964, updated on 17-Aug-2024

Summary

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Official Symbol
Iqank1provided by MGI
Official Full Name
IQ motif and ankyrin repeat containing 1provided by MGI
Primary source
MGI:MGI:3588184
See related
Ensembl:ENSMUSG00000102018 AllianceGenome:MGI:3588184
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
4933407E14Rik; K230010J24Rik
Summary
Orthologous to human IQANK1 (IQ motif and ankyrin repeat containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 22.0), genital fat pad adult (RPKM 3.3) and 3 other tissues See more
Orthologs
human all
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Genomic context

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Location:
15 D3; 15 35.23 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (75881320..75918830)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (76009435..76046981)

Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 166 Neighboring gene mitogen-activated protein kinase 15 Neighboring gene family with sequence similarity 83, member H Neighboring gene scribbled planar cell polarity Neighboring gene microRNA 6952 Neighboring gene STARR-seq mESC enhancer starr_39038 Neighboring gene poly-U binding splicing factor 60

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
  3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

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Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  

General protein information

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Preferred Names
IQ motif and ankyrin repeat domain-containing protein 1
Names
putative IQ motif and ankyrin repeat domain-containing protein LOC642574 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001370920.1 → NP_001357849.1  IQ motif and ankyrin repeat domain-containing protein 1

    Status: VALIDATED

    Source sequence(s)
    AC116487
    Consensus CDS
    CCDS88783.1
    UniProtKB/Swiss-Prot
    A0A140LHX0, Q3TYL0
    UniProtKB/TrEMBL
    A0A7D9N0L4
    Related
    ENSMUSP00000146582.2, ENSMUST00000187868.3
    Conserved Domains (5) summary
    pfam05262
    Location:287 → 400
    Borrelia_P83; Borrelia P83/100 protein
    COG0666
    Location:192 → 314
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:191 → 222
    ANK; ANK repeat [structural motif]
    pfam12781
    Location:427 → 479
    AAA_9; ATP-binding dynein motor region D5
    pfam13637
    Location:192 → 245
    Ank_4; Ankyrin repeats (many copies)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000081.7 Reference GRCm39 C57BL/6J

    Range
    75881320..75918830
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030248636.2 → XP_030104496.1  IQ motif and ankyrin repeat domain-containing protein 1 isoform X4

    Conserved Domains (2) summary
    pfam12781
    Location:143 → 193
    AAA_9; ATP-binding dynein motor region D5
    NF033930
    Location:8 → 125
    pneumo_PspA; pneumococcal surface protein A

  2. XM_030248629.2 → XP_030104489.1  IQ motif and ankyrin repeat domain-containing protein 1 isoform X1

    UniProtKB/Swiss-Prot
    A0A140LHX0, Q3TYL0
    UniProtKB/TrEMBL
    A0A7D9N0L4
    Conserved Domains (5) summary
    pfam05262
    Location:287 → 400
    Borrelia_P83; Borrelia P83/100 protein
    COG0666
    Location:192 → 314
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:191 → 222
    ANK; ANK repeat [structural motif]
    pfam12781
    Location:427 → 479
    AAA_9; ATP-binding dynein motor region D5
    pfam13637
    Location:192 → 245
    Ank_4; Ankyrin repeats (many copies)

  3. XM_036159485.1 → XP_036015378.1  IQ motif and ankyrin repeat domain-containing protein 1 isoform X4

    Conserved Domains (2) summary
    pfam12781
    Location:143 → 193
    AAA_9; ATP-binding dynein motor region D5
    NF033930
    Location:8 → 125
    pneumo_PspA; pneumococcal surface protein A

  4. XM_036159484.1 → XP_036015377.1  IQ motif and ankyrin repeat domain-containing protein 1 isoform X4

    Conserved Domains (2) summary
    pfam12781
    Location:143 → 193
    AAA_9; ATP-binding dynein motor region D5
    NF033930
    Location:8 → 125
    pneumo_PspA; pneumococcal surface protein A

  5. XM_030248634.1 → XP_030104494.1  IQ motif and ankyrin repeat domain-containing protein 1 isoform X3

    Conserved Domains (2) summary
    pfam05262
    Location:36 → 149
    Borrelia_P83; Borrelia P83/100 protein
    pfam12781
    Location:176 → 228
    AAA_9; ATP-binding dynein motor region D5

  6. XM_036159483.1 → XP_036015376.1  IQ motif and ankyrin repeat domain-containing protein 1 isoform X2

    UniProtKB/Swiss-Prot
    A0A140LHX0, Q3TYL0
    Conserved Domains (5) summary
    COG0666
    Location:170 → 292
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    sd00045
    Location:169 → 200
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:170 → 223
    Ank_4; Ankyrin repeats (many copies)
    pfam12781
    Location:405 → 455
    AAA_9; ATP-binding dynein motor region D5
    NF033930
    Location:237 → 387
    pneumo_PspA; pneumococcal surface protein A

RNA

  1. XR_004938850.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3TYL0.3 GenPept UniProtKB/Swiss-Prot:Q3TYL0

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